Exploring bubble oscillation and mass transfer enhancement in acoustic-assisted liquid-liquid extraction with a microfluidic device

Yuliang Xie; Chandraprakash Chindam; Nitesh Nama; Shikuan Yang; Mengqian Lu; Yanhui Zhao; John D Mai; Francesco Costanzo; Tony Jun Huang

doi:10.1038/srep12572

Back

Exploring bubble oscillation and mass transfer enhancement in acoustic-assisted liquid-liquid extraction with a microfluidic device

Journal article

Open access

Peer reviewed

Exploring bubble oscillation and mass transfer enhancement in acoustic-assisted liquid-liquid extraction with a microfluidic device

Yuliang Xie, Chandraprakash Chindam, Nitesh Nama, Shikuan Yang, Mengqian Lu, Yanhui Zhao, John D Mai, Francesco Costanzo and Tony Jun Huang

Scientific reports, Vol.5(1), pp.12572-12572

07/30/2015

DOI: 10.1038/srep12572

PMCID: PMC4519785

PMID: 26223474

Files and links (1)

url

https://doi.org/10.1038/srep12572View

Published (Version of record) Open Access

Abstract

We investigated bubble oscillation and its induced enhancement of mass transfer in a liquid-liquid extraction process with an acoustically-driven, bubble-based microfluidic device. The oscillation of individually trapped bubbles, of known sizes, in microchannels was studied at both a fixed frequency, and over a range of frequencies. Resonant frequencies were analytically identified and were found to be in agreement with the experimental observations. The acoustic streaming induced by the bubble oscillation was identified as the cause of this enhanced extraction. Experiments extracting Rhodanmine B from an aqueous phase (DI water) to an organic phase (1-octanol) were performed to determine the relationship between extraction efficiency and applied acoustic power. The enhanced efficiency in mass transport via these acoustic-energy-assisted processes was confirmed by comparisons against a pure diffusion-based process.

Acoustics

Algorithms

1-Octanol - chemistry

Diffusion

Liquid-Liquid Extraction

Microfluidic Analytical Techniques - instrumentation

Microfluidic Analytical Techniques - methods

Rhodamines - chemistry

Rhodamines - isolation & purification

Water - chemistry

Details

Title: Subtitle: Exploring bubble oscillation and mass transfer enhancement in acoustic-assisted liquid-liquid extraction with a microfluidic device
Creators: Yuliang Xie - Pennsylvania State University
Chandraprakash Chindam - Pennsylvania State University
Nitesh Nama - Pennsylvania State University
Shikuan Yang - Pennsylvania State University
Mengqian Lu - Pennsylvania State University
Yanhui Zhao - Pennsylvania State University
John D Mai - City University of Hong Kong
Francesco Costanzo - Pennsylvania State University
Tony Jun Huang - Pennsylvania State University
Resource Type: Journal article
Publication Details: Scientific reports, Vol.5(1), pp.12572-12572
DOI: 10.1038/srep12572
PMID: 26223474
PMCID: PMC4519785
NLM abbreviation: Sci Rep
ISSN: 2045-2322
eISSN: 2045-2322
Grant note: R01 GM112048 / NIGMS NIH HHS 1 R01 GM112048-01A1 / NIGMS NIH HHS 1R33EB019785-01 / NIBIB NIH HHS R33 EB019785 / NIBIB NIH HHS
Language: English
Date published: 07/30/2015
Academic Unit: Roy J. Carver Department of Biomedical Engineering
Record Identifier: 9984197004402771

Metrics

6 Record Views

38 Times Cited - Web of Science