Exploring the optimal site for the localization of dorsolateral prefrontal cortex in brain stimulation experiments

Paul B. Fitzgerald; Jerome J. Maller; Kate E. Hoy; Richard Thomson; Zafiris J. Daskalakis

doi:10.1016/j.brs.2009.03.002

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Exploring the optimal site for the localization of dorsolateral prefrontal cortex in brain stimulation experiments

Journal article

Peer reviewed

Exploring the optimal site for the localization of dorsolateral prefrontal cortex in brain stimulation experiments

Paul B. Fitzgerald, Jerome J. Maller, Kate E. Hoy, Richard Thomson and Zafiris J. Daskalakis

Brain stimulation, Vol.2(4), pp.234-237

10/01/2009

DOI: 10.1016/j.brs.2009.03.002

PMID: 20633422

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https://doaj.org/article/cc161759de224e8291015a74b4681683View

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Abstract

Background Dorsolateral prefrontal cortex (DLPFC) is a common target for repetitive transcranial magnetic stimulation (rTMS) experiments and therapeutic protocols. Objective The aim of this study was to investigate the optimal method for the localization of DLPFC for use in these studies. Methods Twelve healthly subjects underwent a structural magnetic resonance imaging (MRI) scan, a TMS procedure to establish the location of the motor cortex and a neuronavigational procedure to assess the relative position of the DLPFC. Several electroencephalographic (EEG) points and a position 5 cm anterior to motor cortex were established. Results The DLPFC site used was identified as being approximately halfway between the EEG points F3 and AF3. This point is considerably more anterior than the point identified by measuring 5 cm anterior to motor cortex. Conclusions EEG points provide a useful way to optimally identify DLPFC. (C) 2009 Elsevier Inc. All rights reserved.

Clinical Neurology

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Title: Subtitle: Exploring the optimal site for the localization of dorsolateral prefrontal cortex in brain stimulation experiments
Creators: Paul B. Fitzgerald - Monash Alfred Psychiatry Research centre
Jerome J. Maller - Monash Alfred Psychiatry Research centre
Kate E. Hoy - Monash Alfred Psychiatry Research centre
Richard Thomson - The Alfred Hospital
Zafiris J. Daskalakis - Centre for Addiction and Mental Health
Resource Type: Journal article
Publication Details: Brain stimulation, Vol.2(4), pp.234-237
DOI: 10.1016/j.brs.2009.03.002
PMID: 20633422
NLM abbreviation: Brain Stimul
ISSN: 1935-861X
eISSN: 1876-4754
Publisher: Elsevier
Number of pages: 4
Grant note: Neurosciences Australia Clinical Neurobiology of Psychiatry Platform 436710 / National Health and Medical Research Council (NHMRC); National Health & Medical Research Council (NHMRC) of Australia
Language: English
Date published: 10/01/2009
Academic Unit: Radiology
Record Identifier: 9984848429102771

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