Journal article
Exposures of human volunteers to a controlled atmospheric mixture of ozone, sulfur dioxide and sulfuric acid
American Industrial Hygiene Association journal, Vol.42(1), pp.61-69
01/1981
DOI: 10.1080/15298668191419361
PMID: 7223637
Abstract
Nineteen human volunteers with normal pulmonary function and no history of asthma were exposed on two separate days to clean air and to an atmospheric mixture containing ozone (O3), 0.37 ppm, sulfur dioxide (SO2), 0.37 ppm, and sulfuric acid aerosol (B2SO4), 100 micrograms/m3. Subjects were exposed under carefully controlled conditions for two hours. During this period, the subjects alternately exercised for 15 minutes, at a level calculated to double minute ventilation, and rested for 15 minutes. The experimental goal was to determine whether the presence of the copollutants, H2SO4 and SO2, would significantly enhance the irritant potential of ozone, or cause decrements in pulmonary function on the order of 10 - 20 percent. Statistical analysis of the group averaged data suggested that the mixture may have been slightly more irritating to the subjects than was O3 alone. A large percentage of the subjects exhibited small decrements in pulmonary function. The group averaged FEV1.0 (forced expiratory volume in one second) on the exposure day was depressed 3.7 percent from the control value. One might expect O3 alone to depress FEV1.0 by about 2.8 percent under similar exposure conditions.
Details
- Title: Subtitle
- Exposures of human volunteers to a controlled atmospheric mixture of ozone, sulfur dioxide and sulfuric acid
- Creators
- Michael T KleinmanRonald M BaileyYuan-Tai C ChangKenneth W ClarkMichael P JonesWilliam S LinnJack D Hackney
- Resource Type
- Journal article
- Publication Details
- American Industrial Hygiene Association journal, Vol.42(1), pp.61-69
- Publisher
- United States
- DOI
- 10.1080/15298668191419361
- PMID
- 7223637
- ISSN
- 0002-8894
- eISSN
- 2163-369X
- Language
- English
- Date published
- 01/1981
- Academic Unit
- Statistics and Actuarial Science; Biostatistics; Public Policy Center (Archive)
- Record Identifier
- 9983985871902771
Metrics
24 Record Views