Expression of hydra head activator in newt tissues and effects on limb regeneration

E J Fuentes; A L Mescher; R Ekman; P A Tsonis

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Expression of hydra head activator in newt tissues and effects on limb regeneration

Journal article

Peer reviewed

Expression of hydra head activator in newt tissues and effects on limb regeneration

E J Fuentes, A L Mescher, R Ekman and P A Tsonis

In vivo (Athens), Vol.7(1), pp.59-63

01/1993

PMID: 8389215

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Abstract

In this study, the presence of the hydra head activator (HHA) neuropeptide and its influence on regenerating newt limbs (Notophthalmus viridescens) was investigated. Immunohistological analysis has localized the HHA neuropeptide in the adult newt brain, eye, intestine, and regenerating blastema. Experiments in which 9 day limb regenerates were denervated and subsequently implanted with HHA-soaked beads suggest a slight progression of blastema growth compared to denervated controls.

Immunohistochemistry

Neuropeptides - analysis

Amino Acid Sequence

Salamandridae - metabolism

Eye - chemistry

Intestines - chemistry

Molecular Sequence Data

Pyrrolidonecarboxylic Acid - analogs & derivatives

Regeneration - physiology

Brain Chemistry - physiology

Cell Division - physiology

Animals

Cyclic GMP - metabolism

Extremities - physiology

Cyclic AMP - metabolism

Details

Title: Subtitle: Expression of hydra head activator in newt tissues and effects on limb regeneration
Creators: E J Fuentes - Department of Biology, University of Dayton, OH 45469-2320
A L Mescher
R Ekman
P A Tsonis
Resource Type: Journal article
Publication Details: In vivo (Athens), Vol.7(1), pp.59-63
Publisher: Greece
PMID: 8389215
ISSN: 0258-851X
eISSN: 1791-7549
Language: English
Date published: 01/1993
Academic Unit: Biochemistry and Molecular Biology
Record Identifier: 9984024418402771

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