Journal article
External Quality Assurance Performance of Clinical Research Laboratories in Sub-Saharan Africa
American journal of clinical pathology, Vol.138(5), pp.720-723
2012
DOI: 10.1309/AJCP8PCM4JVLEEQR
PMID: 23086773
Abstract
Patient Safety Monitoring in International Laboratories (JHU-SMILE) is a resource at Johns Hopkins University that supports and monitors laboratories in National Institutes of Health–funded international clinical trials. To determine the impact of the JHU-SMILE quality assurance scheme in sub-Saharan African laboratories, we reviewed 40 to 60 months of external quality assurance (EQA) results of the College of American Pathologists (CAP) in these laboratories. We reviewed the performance of 8 analytes: albumin, alanine aminotransferase, creatinine, sodium, WBC, hemoglobin, hematocrit, and the human immunodeficiency virus antibody rapid test. Over the 40- to 60-month observation period, the sub-Saharan laboratories had a 1.63% failure rate, which was 40% lower than the 2011 CAP-wide rate of 2.8%. Seventy-six percent of the observed EQA failures occurred in 4 of the 21 laboratories. These results demonstrate that a system of remote monitoring, feedback, and audits can support quality in low-resource settings, even in places without strong regulatory support for laboratory quality.
Details
- Title: Subtitle
- External Quality Assurance Performance of Clinical Research Laboratories in Sub-Saharan Africa
- Creators
- Timothy K AMUKELE - Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, United StatesKurt MICHAEL - Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, United StatesMary HANES - Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, United StatesRobert E MILLER - Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, United StatesJ Brooks Jackson - Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, United States
- Resource Type
- Journal article
- Publication Details
- American journal of clinical pathology, Vol.138(5), pp.720-723
- Publisher
- American Society of Clinical Pathologists; Chicago, IL
- DOI
- 10.1309/AJCP8PCM4JVLEEQR
- PMID
- 23086773
- ISSN
- 0002-9173
- eISSN
- 1943-7722
- Language
- English
- Date published
- 2012
- Academic Unit
- Pathology; VPMA - Administration
- Record Identifier
- 9984046813302771
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