Journal article
Extra cytoplasmic function σ factor activation
Current opinion in microbiology, Vol.15(2), pp.182-188
04/2012
DOI: 10.1016/j.mib.2012.01.001
PMCID: PMC3320685
PMID: 22381678
Abstract
The bacterial cell envelope is essential for cell viability and is a target for numerous antibiotics and host immune defenses. Thus bacteria must sense and respond to damage to the cell envelope. Many bacteria utilize alternative σ factors such as extracytoplasmic function (ECF) σ factors to respond to cell envelope stress. Although ECF σ factors are utilized by both Gram negative and Gram positive bacteria to respond to cell envelope stress, the mechanisms of sensing differ. In this review, we examine the events and proteins that are required for activation of two model extracytoplasmic function σ factors, σ(E) in E. coli and σ(W) in B. subtilis.
Details
- Title: Subtitle
- Extra cytoplasmic function σ factor activation
- Creators
- Theresa D Ho - Department of Microbiology, University of Iowa, Iowa City, IA 52242, United StatesCraig D Ellermeier
- Resource Type
- Journal article
- Publication Details
- Current opinion in microbiology, Vol.15(2), pp.182-188
- DOI
- 10.1016/j.mib.2012.01.001
- PMID
- 22381678
- PMCID
- PMC3320685
- NLM abbreviation
- Curr Opin Microbiol
- ISSN
- 1369-5274
- eISSN
- 1879-0364
- Grant note
- R01 AI087834 / NIAID NIH HHS R01 AI087834-01A1 / NIAID NIH HHS AI087834 / NIAID NIH HHS
- Language
- English
- Date published
- 04/2012
- Academic Unit
- Microbiology and Immunology
- Record Identifier
- 9984083877702771
Metrics
12 Record Views