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Extraction of Airways From CT (EXACT'09)
Journal article   Open access   Peer reviewed

Extraction of Airways From CT (EXACT'09)

Pechin Lo, Joseph M Reinhardt, Bram van Ginneken, Christian Bauer, Reinhard Beichel, Tarunashree Yavarna, Eric A Hoffman, Pim A de Jong, Benjamin Irving, Catalin Fetita, …
IEEE transactions on medical imaging, Vol.31(11), pp.2093-2107
11/2012
DOI: 10.1109/TMI.2012.2209674
PMID: 22855226
url
https://doi.org/10.1109/TMI.2012.2209674View
Published (Version of record) Open Access

Abstract

This paper describes a framework for establishing a reference airway tree segmentation, which was used to quantitatively evaluate 15 different airway tree extraction algorithms in a standardized manner. Because of the sheer difficulty involved in manually constructing a complete reference standard from scratch, we propose to construct the reference using results from all algorithms that are to be evaluated. We start by subdividing each segmented airway tree into its individual branch segments. Each branch segment is then visually scored by trained observers to determine whether or not it is a correctly segmented part of the airway tree. Finally, the reference airway trees are constructed by taking the union of all correctly extracted branch segments. Fifteen airway tree extraction algorithms from different research groups are evaluated on a diverse set of 20 chest computed tomography (CT) scans of subjects ranging from healthy volunteers to patients with severe pathologies, scanned at different sites, with different CT scanner brands, models, and scanning protocols. Three performance measures covering different aspects of segmentation quality were computed for all participating algorithms. Results from the evaluation showed that no single algorithm could extract more than an average of 74% of the total length of all branches in the reference standard, indicating substantial differences between the algorithms. A fusion scheme that obtained superior results is presented, demonstrating that there is complementary information provided by the different algorithms and there is still room for further improvements in airway segmentation algorithms.
Computed Tomography evaluation Image segmentation Lungs Medical diagnostic imaging pulmonary airways segmentation

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