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FAVORABLE PROGNOSIS IN METASTATIC ADRENAL CARCINOMA: AN UNEXPECTED OUTCOME
Journal article   Open access   Peer reviewed

FAVORABLE PROGNOSIS IN METASTATIC ADRENAL CARCINOMA: AN UNEXPECTED OUTCOME

Aisha Sheikh and Imran Hassan
Endocrine practice, Vol.25, pp.23-23
04/01/2019
DOI: 10.47391/JPMA.3494
url
https://doi.org/10.47391/JPMA.3494View
Published (Version of record) Open Access

Abstract

The case of a 45-year-old male patient diagnosed with European Network for the Study of Adrenal Tumours (ENSAT) criteria, stage IV adrenocortical carcinoma (ACC) with unexpectedly prolonged survival is being reported. The patient underwent resection of stage IV ACC and despite suboptimal adherence to postoperative mitotane and chemotherapy, had a prolonged survival spanning almost seven years. The possible reasons for such an outcome are discussed. ACC is a rare tumour with stage 4 disease known to be associated with a particularly grim prognosis. A low grade on histology (mitotic index 11-12 per 50 HPF) was likely responsible for the prolonged survival of our patient. Low grade disease may predict extended survival in stage IV ACC.
Chemotherapy Metastasis Tumors Medical prognosis

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