Journal article
FDG-PET Lymphoma Demonstration Project Invitational Workshop
Academic radiology, Vol.14(3), pp.330-339
2007
DOI: 10.1016/j.acra.2006.12.003
PMID: 17307666
Abstract
The proceedings of a workshop focusing on a project to evaluate the use of fluorodeoxyglucose-positron emission tomography (FDG-PET) as a tool to measure treatment response in non-Hodgkin lymphoma (NHL) are described. Sponsored by the Leukemia & Lymphoma Society, the Foundation of the National Institutes of Health, and the National Cancer Institute, and attended by representatives of the Food and Drug Administration, the Centers for Medicare and Medicaid Services, and scientists and clinical researchers from academia and the pharmaceutical and medical imaging industries, the workshop reviewed the etiology and current standards of care for NHL and proposed the development of a clinical trial to validate FDG-PET imaging techniques as a predictive biomarker for cancer therapy response. As organized under the auspices of the Oncology Biomarker Qualification Initiative, the three federal health agencies and their private sector and nonprofit/advocacy group partners believe that FDG-PET not only demonstrates the potential to be used for the diagnosis and staging of many cancers but in particular can provide an early indication of therapeutic response that is well correlated with clinical outcomes for chemotherapy for this common form of lymphoma. The development of standardized criteria for FDG-PET imaging and establishment of procedures for transmission, storage, quality assurance, and analysis of PET images afforded by this demonstration project could streamline clinical trials of new treatments for more intractable forms of lymphoma and other cancers and, hence, accelerate new drug approvals.
Details
- Title: Subtitle
- FDG-PET Lymphoma Demonstration Project Invitational Workshop
- Creators
- Gary J. Kelloff - National Institutes of HealthDaniel M. Sullivan - National Institutes of HealthWyndham Wilson - National Institutes of HealthBruce Cheson - National Institutes of HealthMalik Juweid - National Institutes of HealthGeorge Q. Mills - Memorial Sloan Kettering Cancer CenterAndrew D. Zelenetz - National Institutes of HealthSandra J. Horning - National Institutes of HealthWolfgang Weber - Mayo Clinic Rochester MNDaniel J. Sargent - Mayo ClinicLori Dodd - National Institutes of HealthEdward Korn - National Institutes of HealthJames Armitage - University of Nebraska at OmahaRichard Schilsky - Johns Hopkins UniversityMichaele Christian - National Institutes of HealthOwen A. O’Connor - Memorial Sloan-Kettering Cancer Center, New York City, NYSue Jane Wang - Memorial Sloan Kettering Cancer CenterAnn T. Farrell - Memorial Sloan Kettering Cancer CenterRichard Pazdur - Memorial Sloan Kettering Cancer CenterMichael Graham - National Institutes of HealthRichard L. Wahl - Johns Hopkins UniversitySteven M. Larson - National Institutes of HealthLale Kostakoglu - National Institutes of HealthMargaret Daube-Witherspoon - Brown UniversityConstantine Gastonis - National Institutes of HealthBarry A. Siegel - Washington University in St. LouisLalitha K. Shankar - National Institutes of HealthDavid B. Lee - National Institutes of HealthHoward R. Higley - CCS AssociatesCaroline C. Sigman - CCS AssociatesDaniel Carucci - National Institutes of HealthDavid Timko - National Institutes of HealthLouis J. deGennaro - National Institutes of HealthEllen Sigal - National Institutes of HealthAnna Barker - National Institutes of HealthJanet Woodcock - Memorial Sloan Kettering Cancer Center
- Resource Type
- Journal article
- Publication Details
- Academic radiology, Vol.14(3), pp.330-339
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.acra.2006.12.003
- PMID
- 17307666
- ISSN
- 1076-6332
- eISSN
- 1878-4046
- Language
- English
- Date published
- 2007
- Academic Unit
- Radiology; Radiation Oncology; Internal Medicine
- Record Identifier
- 9984313082702771
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