FLOW DYNAMIC COMPARISON BETWEEN RECESSED HINGE AND OPEN PIVOT BI-LEAFLET HEART VALVE DESIGNS

V Govindarajan; H.S Udaykumar; K.B Chandran

doi:10.1142/S0219519409002912

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FLOW DYNAMIC COMPARISON BETWEEN RECESSED HINGE AND OPEN PIVOT BI-LEAFLET HEART VALVE DESIGNS

Journal article

Peer reviewed

FLOW DYNAMIC COMPARISON BETWEEN RECESSED HINGE AND OPEN PIVOT BI-LEAFLET HEART VALVE DESIGNS

V Govindarajan, H.S Udaykumar and K.B Chandran

Journal of mechanics in medicine and biology, Vol.9(2), pp.161-176

06/01/2009

DOI: 10.1142/S0219519409002912

PMCID: PMC2768291

PMID: 19865586

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https://www.ncbi.nlm.nih.gov/pmc/articles/2768291View

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Abstract

The flow dynamics through the peripheral and hinge regions of a bi-leaflet mechanical heart valve are complex and result in abnormally high shear stresses particularly during the closing phase of the valve function. It has been observed that, the late stages of closure is more significant in the dynamics of platelet activation; therefore, the later stages of closure is simulated by solving the two-dimensional Navier–Stokes equations using an Eulerian Levelset based sharp interface Cartesian grid method. Using a fixed Cartesian mesh incorporating local mesh refinement for solution accuracy and efficiency, the flow through and within a recessed hinge design and an open pivot hinge design is compared. Platelets are modelled as point particles by Lagrangian particle tracking algorithm with one way coupling. A dilute particle flow is assumed and particle-particle interactions are neglected. It was observed that the hinge region of the open pivot valve indicated a lower potential for activation of platelets compared to that in valves with a recessed hinge design.

Recessed hinge design

Open pivot design

Platelet activation parameter

Details

Title: Subtitle: FLOW DYNAMIC COMPARISON BETWEEN RECESSED HINGE AND OPEN PIVOT BI-LEAFLET HEART VALVE DESIGNS
Creators: V Govindarajan - Department of Biomedical Engineering, The University of Iowa, Iowa City, IA-52242
H.S Udaykumar - Department of Mechanical and Industrial Engineering, The University of Iowa, Iowa City, IA-52242
K.B Chandran - Department of Biomedical Engineering, The University of Iowa, Iowa City, IA-52242
Resource Type: Journal article
Publication Details: Journal of mechanics in medicine and biology, Vol.9(2), pp.161-176
DOI: 10.1142/S0219519409002912
PMID: 19865586
PMCID: PMC2768291
NLM abbreviation: J Mech Med Biol
ISSN: 0219-5194
eISSN: 1793-6810
Language: English
Date published: 06/01/2009
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Injury Prevention Research Center; Mechanical Engineering
Record Identifier: 9984064112502771

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