Journal article
Factors Associated With Treatment and Control of Hypertension in a Healthy Elderly Population Free o Cardiovascular Disease: A Cross-sectional Study
American journal of hypertension, Vol.33(4), pp.350-361
04/01/2020
DOI: 10.1093/ajh/hpz192
PMCID: PMC7109352
PMID: 31807750
Abstract
BACKGROUND
Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt cardiovascular disease (CVD), and identified factors related to both "untreated" and "treated but uncontrolled" high BP.
METHODS
We analyzed baseline data from 19,114 individuals aged >= 65 years enrolled from Australia and United States (US) in the ASPirin in Reducing Events in the Elderly study. Hypertension was defined as an average systolic/diastolic BP >= 140/90 mm Hg and/or the use of any BP lowering medication."Controlled hypertension" was defined if participants were receiving antihypertensive medication and BP <140 and 90 mm Hg. Descriptive analyses were used to summarize hypertension control rates; logistic regression was used to investigate relationships with treatment and BP control.
RESULTS
Overall, 74% (14,213/19,114) of participants were hypertensive; and of these 29% (4,151/14,213) were untreated. Among those treated participants, 53% (5,330/10,062) had BP >= 140/90 mm Hg. Participants who were untreated were more likely to be men, have higher educational status, and be in good physical health,and less likely to have significant comorbidities. The factors related to "treated but uncontrolled" BP included older age, male, Black race (vs. White), using antihypertensive monotherapy (vs. multiple) and residing in Australia (vs. US).
CONCLUSIONS
High levels of 'untreated" and "treated but uncontrolled" BP occur in healthy elderly people without CVD, suggesting there are opportunities for better BP control in the primary prevention of CVD in this population.
Details
- Title: Subtitle
- Factors Associated With Treatment and Control of Hypertension in a Healthy Elderly Population Free o Cardiovascular Disease: A Cross-sectional Study
- Creators
- Enayet K. Chowdhury - Monash UniversityMark R. Nelson - Monash UniversityMichael E. Ernst - University of IowaKaren L. Margolis - HealthPartnersLawrence J. Beilin - Royal Perth HospitalColin I. Johnston - Baker Heart and Diabetes InstituteRobyn L. Woods - Monash UniversityAnne M. Murray - Hennepin Healthcare Research InstituteRory Wolfe - Monash UniversityElsdon Storey - Monash UniversityRaj C. Shah - Rush University Medical CenterJessica E. Lockery - Monash UniversityAndrew M. Tonkin - Monash UniversityAnne B. Newman - University of PittsburghJeff D. Williamson - Wake Forest UniversityWalter P. Abhayaratna - Australian National UniversityNigel P. Stocks - University of AdelaideSharyn M. Fitzgerald - Monash UniversitySuzanne G. Orchard - Monash UniversityRuth E. Trevaks - Monash UniversityGeoffrey A. Donnan - Florey Institute of Neuroscience and Mental HealthRichard Grimm - Hennepin Healthcare Research InstituteJohn J. McNeil - Monash UniversityChristopher M. Reid - Monash UniversityASPREE Investigator Group
- Resource Type
- Journal article
- Publication Details
- American journal of hypertension, Vol.33(4), pp.350-361
- Publisher
- Oxford Univ Press
- DOI
- 10.1093/ajh/hpz192
- PMID
- 31807750
- PMCID
- PMC7109352
- ISSN
- 0895-7061
- eISSN
- 1879-1905
- Number of pages
- 12
- Grant note
- U01AG029824 / National Cancer Institute at the National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) National Institute on Aging; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) Victorian Cancer Agency (Australia) 334047; 1127060 / National Health and Medical Research Council; National Health and Medical Research Council (NHMRC) of Australia Monash University (Australia); Monash University
- Language
- English
- Date published
- 04/01/2020
- Academic Unit
- Family and Community Medicine; Pharmacy Practice and Science
- Record Identifier
- 9984297343602771
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