Journal article
Factors Associated With the Choice of Radiation Therapy Treatment Facility in Head and Neck Cancer
The Laryngoscope, Vol.131(5), pp.1019-1025
05/01/2021
DOI: 10.1002/lary.29033
PMCID: PMC7907264
PMID: 32846018
Abstract
Objective To analyze the clinicodemographic characteristics and treatment outcomes of patients receiving postoperative radiation therapy (PORT) at a different treatment facility rather than the initial surgical facility for head and neck cancer. Study Design:Retrospective cohort analysis. Methods Utilizing the National Cancer Data Base, 2004 to 2015, patients with a diagnosis of oral cavity/oropharyngeal, hypopharyngeal, and laryngeal squamous cell carcinoma were studied. Multivariate analysis was completed with multivariate regression and Cox proportional hazard model, and survival outcomes were examined using Kaplan-Meier analysis. Results A total of 15,181 patients who had surgery for a head and neck cancer at an academic/research center were included in the study population. Of the study population, 4,890 (32.2%) patients completed PORT at a different treatment facility. Treatment at a different facility was more common among patients who were >= 65 years old, white, Medicare recipients, those with a greater distance between residence and surgical treatment facility, and with lower income within area of residence (eachP < .05). Overall survival was worse in patients completing PORT at a different treatment facility versus at the institution where surgery was completed (61.9% vs. 66.4%;P= .002). Conclusions PORT at a different facility was more common in older individuals, Medicare recipients, those with greater distance to travel, and lower-income individuals. Completing PORT outside the hospital where surgery was performed was associated with inferior survival outcomes among head and neck cancer patients. Level of Evidence 3Laryngoscope, 2020
Details
- Title: Subtitle
- Factors Associated With the Choice of Radiation Therapy Treatment Facility in Head and Neck Cancer
- Creators
- Christopher B. Sullivan - University of Iowa Hospitals and ClinicsZaid Al-Qurayshi - University of Iowa Hospitals and ClinicsCarryn M. Anderson - University of Iowa Hospitals and ClinicsAaron T. Seaman - University of Iowa Hospitals and ClinicsNitin A. Pagedar - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- The Laryngoscope, Vol.131(5), pp.1019-1025
- DOI
- 10.1002/lary.29033
- PMID
- 32846018
- PMCID
- PMC7907264
- NLM abbreviation
- Laryngoscope
- ISSN
- 0023-852X
- eISSN
- 1531-4995
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- P30CA086862 / National Cancer Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) UL1TR002537 / National Center for Advancing Translational Sciences; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Advancing Translational Sciences (NCATS) 5T32DC000040 / National Institutes of Health, Institutional National Research Award: T32; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Language
- English
- Date published
- 05/01/2021
- Academic Unit
- Radiation Oncology; Center for Social Science Innovation; General Internal Medicine; Community and Behavioral Health; Otolaryngology; Internal Medicine
- Record Identifier
- 9984312249502771
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