Journal article
Factors Impacting Fertility Preservation in Adolescents and Young Adults with Cancer: A Retrospective Study
Journal of adolescent and young adult oncology, Vol.9(2), pp.208-221
04/01/2020
DOI: 10.1089/jayao.2019.0100
PMCID: PMC7360112
PMID: 31651207
Abstract
Purpose:
Fertility preservation before therapy is underutilized for those diagnosed with cancer as an adolescent or young adult (AYA). The purpose of this study was to describe factors impacting utilization of fertility preservation consultations and procedures among AYAs at the University of Iowa Health Care (UIHC).
Methods:
Patients were identified by the oncology registry at UIHC. Disease site, histology, date of diagnosis, sex, race, ethnicity, insurance, and zip code data were gathered by the registrars. UIHC's electronic medical record was queried for fertility preservation consultation. The Reproductive Endocrinology and Infertility clinical database captured information about patients who underwent fertility preservation. Rural-urban commuting area codes measured rurality. Descriptive statistics and multivariate linear probability models were used to predict the probability of fertility preservation consultation and procedure.
Results:
From 2008 to 2017, 2932 AYAs were treated for an invasive malignancy at UIHC. Of the 440 (15%) who received a fertility preservation consultation, 156 (5%) underwent a fertility preservation procedure. Multivariate analyses showed that AYAs with public insurance coverage, those diagnosed with central nervous system (CNS) disease or melanoma, and those >30 years old at diagnosis had a significant decrease in the percentage point probability of having a consultation. The percentage point probability of undergoing a procedure was decreased for female patients, those with melanoma or carcinoma, those seen by a pediatric-based provider, and those diagnosed after 25 years of age.
Conclusion:
This study has important implications for practice and policy, particularly regarding insurance coverage and patient and provider characteristics leading to fertility preservation consultations and procedures for AYAs with cancer.
Details
- Title: Subtitle
- Factors Impacting Fertility Preservation in Adolescents and Young Adults with Cancer: A Retrospective Study
- Creators
- Erin M. Mobley - University of IowaGinny L. Ryan - University of IowaAmy E. Sparks - University of IowaVarun Monga - University of IowaWilliam W. Terry - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Journal of adolescent and young adult oncology, Vol.9(2), pp.208-221
- Publisher
- Mary Ann Liebert, Inc., publishers
- DOI
- 10.1089/jayao.2019.0100
- PMID
- 31651207
- PMCID
- PMC7360112
- ISSN
- 2156-5333
- eISSN
- 2156-535X
- Language
- English
- Date published
- 04/01/2020
- Academic Unit
- Health Management and Policy; Hematology, Oncology, and Blood & Marrow Transplantation; Stead Family Department of Pediatrics; Obstetrics and Gynecology; Internal Medicine
- Record Identifier
- 9984318321702771
Metrics
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