Factors Influencing Exercise Following Pancreatic Tumor Resection

Nathan H Parker; Karen Basen-Engquist; M Laura Rubin; Yisheng Li; Laura Prakash; An Ngo-Huang; Jessica Gorzelitz; Naruhiko Ikoma; Jeffrey E Lee; Matthew H G Katz

doi:10.1245/s10434-020-09062-9

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Factors Influencing Exercise Following Pancreatic Tumor Resection

Journal article

Peer reviewed

Factors Influencing Exercise Following Pancreatic Tumor Resection

Nathan H Parker, Karen Basen-Engquist, M Laura Rubin, Yisheng Li, Laura Prakash, An Ngo-Huang, Jessica Gorzelitz, Naruhiko Ikoma, Jeffrey E Lee and Matthew H G Katz

Annals of surgical oncology, Vol.28(4), pp.2299-2309

04/2021

DOI: 10.1245/s10434-020-09062-9

PMID: 32886288

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https://www.ncbi.nlm.nih.gov/pmc/articles/11112718View

Open Access

Abstract

We previously demonstrated associations between exercise during pancreatic cancer treatment and quality of life and physical fitness prior to pancreatectomy. In this study, we quantified exercise among survivors following pancreatic tumor resection and characterized concordance with established guidelines. We quantified exercise frequency, duration, and intensity among survivors who underwent pancreatectomy for adenocarcinoma or a neuroendocrine tumor at our center from 2000 to 2017 and compared them with American College of Sports Medicine Guidelines for Cancer Survivors. Additional surveys measured motivation to exercise, barrier self-efficacy, quality of life, and fatigue. Multivariable models were constructed to evaluate associations between clinicodemographic and psychosocial variables and guideline concordance, and between guideline concordance and quality of life and fatigue. Of 504 eligible survivors, 262 (52%) returned surveys. Only 62 participants (24%) reported meeting both aerobic and strengthening guidelines; 103 (39%) reported meeting neither. Adjusted analyses demonstrated that higher autonomous motivation was associated with higher aerobic and strengthening guideline concordance (both p < 0.01). Higher barrier self-efficacy and older age were associated with higher aerobic guideline concordance (p < 0.01). We identified no significant associations between guideline concordance and tumor type, time since surgery, or recent cancer therapy (all p > 0.05). We found favorable associations between aerobic guideline concordance and both quality of life and fatigue (both p < 0.001). Less than one-quarter of participants exercised sufficiently to meet national exercise guidelines following pancreatectomy. To maximize exercise and related benefits, interventions should help survivors increase intrinsic motivation and overcome barriers to exercise.

Aged

Cancer Survivors

Exercise

Exercise Therapy

Humans

Pancreatic Neoplasms - surgery

Quality of Life

Survivors

Details

Title: Subtitle: Factors Influencing Exercise Following Pancreatic Tumor Resection
Creators: Nathan H Parker - The University of Texas MD Anderson Cancer Center
Karen Basen-Engquist - The University of Texas MD Anderson Cancer Center
M Laura Rubin - The University of Texas MD Anderson Cancer Center
Yisheng Li - The University of Texas MD Anderson Cancer Center
Laura Prakash - The University of Texas MD Anderson Cancer Center
An Ngo-Huang - The University of Texas MD Anderson Cancer Center
Jessica Gorzelitz - University of Wisconsin–Madison
Naruhiko Ikoma - The University of Texas MD Anderson Cancer Center
Jeffrey E Lee - The University of Texas MD Anderson Cancer Center
Matthew H G Katz - The University of Texas MD Anderson Cancer Center
Resource Type: Journal article
Publication Details: Annals of surgical oncology, Vol.28(4), pp.2299-2309
DOI: 10.1245/s10434-020-09062-9
PMID: 32886288
NLM abbreviation: Ann Surg Oncol
ISSN: 1068-9265
eISSN: 1534-4681
Grant note: P30CA016672 / NIH HHS RP170259 / Cancer Prevention and Research Institute of Texas P30 CA016672 / NCI NIH HHS
Language: English
Date published: 04/2021
Academic Unit: Health, Sport, and Human Physiology
Record Identifier: 9984295025302771

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