Factors associated with excessive bleeding after cardiac surgery: A prospective cohort study

Camila Takao Lopes; Evelise Fadini Reis Brunori; Agueda Maria Ruiz Zimmer Cavalcante; Sue Ann Moorhead; Elizabeth Swanson; Juliana de Lima Lopes; Alba Lucia Bottura Leite de Barros

doi:10.1016/j.hrtlng.2015.09.003

Back

Factors associated with excessive bleeding after cardiac surgery: A prospective cohort study

Journal article

Peer reviewed

Factors associated with excessive bleeding after cardiac surgery: A prospective cohort study

Camila Takao Lopes, Evelise Fadini Reis Brunori, Agueda Maria Ruiz Zimmer Cavalcante, Sue Ann Moorhead, Elizabeth Swanson, Juliana de Lima Lopes and Alba Lucia Bottura Leite de Barros

Heart & lung, Vol.45(1), pp.64-69.e2

01/2016

DOI: 10.1016/j.hrtlng.2015.09.003

PMID: 26481384

Files and links (1)

url

http://dx.doi.org/10.1016/j.hrtlng.2015.09.003View

Open Access

Abstract

To identify factors associated with excessive bleeding (ExB) after cardiac surgery in adults. Excessive bleeding after cardiac surgery must be anticipated for implementation of timely interventions. A prospective cohort study with 323 adults requiring open-chest cardiac surgery. Potential factors associated with ExB were investigated through univariate analysis and logistic regression. The accuracy of the relationship between the independent variables and the outcome was depicted through the receiver-operating characteristic (ROC) curve. The factors associated with ExB included gender, body mass index (BMI), preoperative platelet count, intraoperative heparin doses and intraoperative platelet transfusion. The ROC curve cut-off points were 26.35 for the BMI; 214,000 for the preoperative platelet count, and 6.25 for intraoperative heparin dose. This model had an accuracy = 77.3%, a sensitivity = 81%, and a specificity = 62%. Male gender, BMI, preoperative platelet count, dose of intraoperative heparin >312.5 mg without subsequent platelet transfusion, are factors associated with ExB.

Prospective Studies

Humans

Middle Aged

Risk Factors

Logistic Models

Male

Cardiac Surgical Procedures

Platelet Count

Sensitivity and Specificity

Female

ROC Curve

Aged

Cohort Studies

Details

Title: Subtitle: Factors associated with excessive bleeding after cardiac surgery: A prospective cohort study
Creators: Camila Takao Lopes - Paulista Nursing School, Federal University of São Paulo (EPE-UNIFESP), São Paulo, SP, Brazil; Unversity Hospital, São Paulo University (HU-USP), São Paulo, SP, Brazil. Electronic address: camilatakao@hotmail.com
Evelise Fadini Reis Brunori - Dante Pazzanese Cardiology Institute (IDPC), São Paulo, SP, Brazil
Agueda Maria Ruiz Zimmer Cavalcante - Paulista Nursing School, Federal University of São Paulo (EPE-UNIFESP), São Paulo, SP, Brazil
Sue Ann Moorhead - College of Nursing, the University of Iowa, IA, USA
Elizabeth Swanson - College of Nursing, the University of Iowa, IA, USA
Juliana de Lima Lopes - Paulista Nursing School, Federal University of São Paulo (EPE-UNIFESP), São Paulo, SP, Brazil
Alba Lucia Bottura Leite de Barros - Paulista Nursing School, Federal University of São Paulo (EPE-UNIFESP), São Paulo, SP, Brazil
Resource Type: Journal article
Publication Details: Heart & lung, Vol.45(1), pp.64-69.e2
DOI: 10.1016/j.hrtlng.2015.09.003
PMID: 26481384
NLM abbreviation: Heart Lung
ISSN: 0147-9563
eISSN: 1527-3288
Publisher: United States
Grant note: DOI: 10.13039/501100002322, name: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, award: 249494/2013-2.; DOI: 10.13039/501100003593, name: Conselho Nacional de Desenvolvimento Científico e Tecnológico
Language: English
Date published: 01/2016
Academic Unit: Nursing
Record Identifier: 9984064283102771

Metrics

30 Record Views

20 Times Cited - Web of Science