Factors associated with recurrent postinfarction ventricular tachycardia following ablation

Jakrin Kewcharoen; Narut Prasitlumkum; Sittinop Titichoatrattana; Chutikarn Wittayalikit; Angkawipa Trongtorsak; Chanavuth Kanitsoraphan; Prapaipan Putthapiban; Kittika Poonsombudlert; Pattara Rattanawong; Eugene H. Chung

doi:10.23736/S2724-5683.20.05128-2

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Factors associated with recurrent postinfarction ventricular tachycardia following ablation

Journal article

Peer reviewed

Factors associated with recurrent postinfarction ventricular tachycardia following ablation

Jakrin Kewcharoen, Narut Prasitlumkum, Sittinop Titichoatrattana, Chutikarn Wittayalikit, Angkawipa Trongtorsak, Chanavuth Kanitsoraphan, Prapaipan Putthapiban, Kittika Poonsombudlert, Pattara Rattanawong and Eugene H. Chung

MINERVA CARDIOLOGY AND ANGIOLOGY, Vol.69(1), pp.50-60

02/01/2021

DOI: 10.23736/S2724-5683.20.05128-2

PMID: 32989960

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Abstract

INTRODUCTION: Ablation of ventricular tachycardia is the main therapy for patients with drug-refractory ventricular tachycardia (VT). Although evidence suggests that VT ablation could lower the incidence of recurrent VT, many cases still develop VT in follow-up. In this study, we performed a systematic review and meta-analysis to examine risk factors for recurrent VT in patients with postinfarction VT who underwent VT ablation. EVIDENCE ACQUISITION: We comprehensively searched the databases of MEDLINE and EMBASE from inception to March 2020. Included studies were cohort studies, experimental trials, or randomized controlled trials that evaluate the risk of recurrent VT in postinfarction VT patients who underwent VT ablation. Data from each study were combined using random-effects. EVIDENCE SYNTHESIS: Thirteen studies involving 1803 postinfarction patients who underwent VT ablation were included. Inducibility after the procedure (pooled HR=1.71, P<0.001), lower baseline left ventricular ejection fraction (LVEF) (pooled HR=0.98, P<0.001) and higher baseline New York Heart Association (NYHA) classification (pooled HR=1.34, P=0.003) were significantly associated with VT recurrence during the follow-up. There was no significant association between age, gender or diabetes mellitus and VT recurrence. CONCLUSIONS: Our meta-analysis demonstrated that inducibility after the procedure, lower baseline LVE F and higher baseline NYHA classification were associated with an increased risk of VT recurrence in postinfarction VT patients who underwent VT ablation.

Cardiac & Cardiovascular Systems

Cardiovascular System & Cardiology

Life Sciences & Biomedicine

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Details

Title: Subtitle: Factors associated with recurrent postinfarction ventricular tachycardia following ablation
Creators: Jakrin Kewcharoen - University of Hawaii System
Narut Prasitlumkum - University of Hawaii System
Sittinop Titichoatrattana - Chulalongkorn University
Chutikarn Wittayalikit - Chulalongkorn University
Angkawipa Trongtorsak - Chulalongkorn University
Chanavuth Kanitsoraphan - University of Hawaii System
Prapaipan Putthapiban - Einstein Medical Center Philadelphia
Kittika Poonsombudlert - University of Hawaii System
Pattara Rattanawong - Mayo Clinic in Florida
Eugene H. Chung - Michigan Medicine
Resource Type: Journal article
Publication Details: MINERVA CARDIOLOGY AND ANGIOLOGY, Vol.69(1), pp.50-60
Publisher: Edizioni Minerva Medica
DOI: 10.23736/S2724-5683.20.05128-2
PMID: 32989960
ISSN: 2724-5683
eISSN: 2724-5772
Number of pages: 11
Language: English
Date published: 02/01/2021
Academic Unit: Internal Medicine
Record Identifier: 9984694743702771

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