Journal article
Factors influencing long-term primary cadaveric kidney transplantation--importance of functional renal mass versus avoidance of acute rejections--the Toronto Hospital experience 1985-1997
Clinical transplants, Vol.1998, pp.195-203
01/01/1998
PMID: 10503098
Abstract
1. The 5-year actuarial graft, patient and functional graft survival rates were analyzed in 743 consecutive primary cadaveric kidney transplants from The Toronto Hospital between January 1985-December 1997. 2. Recipient age > or = 55 years, male recipient sex, recipient diabetes mellitus, CIT > 36 hours and delayed graft function were found to significantly decrease patient survival. 3. Recipient age > or = 55 years, sensitization to HLA antigens (peak PRA > 50%), donor/recipient HLA antigen mismatches, CIT > 36 hours, delayed graft, function and 6-month SCr > 200 mumol/L were found to significantly decrease graft survival. 4. Acute rejection episodes had no significant impact on overall 5-year patient or graft survival. 5. The observation that serum creatinine > 200 mumol/L had a major adverse influence on long-term outcome reflects the importance of functional renal mass on graft survival.
Details
- Title: Subtitle
- Factors influencing long-term primary cadaveric kidney transplantation--importance of functional renal mass versus avoidance of acute rejections--the Toronto Hospital experience 1985-1997
- Creators
- C C GeddesE ColeJ WadeD CattranS FentonM RobinetteR StewartA HemmingM CattralA GarciaC J Cardella
- Resource Type
- Journal article
- Publication Details
- Clinical transplants, Vol.1998, pp.195-203
- PMID
- 10503098
- ISSN
- 0890-9016
- Language
- English
- Date published
- 01/01/1998
- Academic Unit
- Surgery
- Record Identifier
- 9984322932402771
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