Journal article
Factors predictive of use and of benefit from continuous glucose monitoring in type 1 diabetes
Diabetes care, Vol.32(11), pp.1947-1953
11/2009
DOI: 10.2337/dc09-0889
PMCID: PMC2768196
PMID: 19675206
Abstract
To evaluate factors associated with successful use of continuous glucose monitoring (CGM) among participants with intensively treated type 1 diabetes in the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Randomized Clinical Trial.
The 232 participants randomly assigned to the CGM group (165 with baseline A1C >or=7.0% and 67 with A1C <7.0%) were asked to use CGM on a daily basis. The associations of baseline factors and early CGM use with CGM use >or=6 days/week in the 6th month and with change in A1C from baseline to 6 months were evaluated in regression models.
The only baseline factors found to be associated with greater CGM use in month 6 were age >or=25 years (P < 0.001) and more frequent self-reported prestudy blood glucose meter measurements per day (P < 0.001). CGM use and the percentage of CGM glucose values between 71 and 180 mg/dl during the 1st month were predictive of CGM use in month 6 (P < 0.001 and P = 0.002, respectively). More frequent CGM use was associated with a greater reduction in A1C from baseline to 6 months (P < 0.001), a finding present in all age-groups.
After 6 months, near-daily CGM use is more frequent in intensively treated adults with type 1 diabetes than in children and adolescents, although in all age-groups near-daily CGM use is associated with a similar reduction in A1C. Frequency of blood glucose meter monitoring and initial CGM use may help predict the likelihood of long-term CGM benefit in intensively treated patients with type 1 diabetes of all ages.
Details
- Title: Subtitle
- Factors predictive of use and of benefit from continuous glucose monitoring in type 1 diabetes
- Creators
- Roy W BeckBruce BuckinghamKellee MillerHoward WolpertDongyuan XingJennifer M BlockH Peter ChaseIrl HirschCraig KollmanLori LaffelJean M LawrenceKerry MilaszewskiKatrina J RuedyWilliam V TamborlaneJuvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group
- Contributors
- Eva Tsalikian (Contributor) - University of Iowa, Stead Family Department of Pediatrics
- Resource Type
- Journal article
- Publication Details
- Diabetes care, Vol.32(11), pp.1947-1953
- DOI
- 10.2337/dc09-0889
- PMID
- 19675206
- PMCID
- PMC2768196
- ISSN
- 0149-5992
- eISSN
- 1935-5548
- Language
- English
- Date published
- 11/2009
- Academic Unit
- Stead Family Department of Pediatrics
- Record Identifier
- 9984093502302771
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