Factors that Differentially Affect Daytime and Nighttime Sleep in Drosophila melanogaster

Hiroshi Ishimoto; Arianna Lark; Toshihiro Kitamoto

doi:10.3389/fneur.2012.00024

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Factors that Differentially Affect Daytime and Nighttime Sleep in Drosophila melanogaster

Journal article

Open access

Peer reviewed

Factors that Differentially Affect Daytime and Nighttime Sleep in Drosophila melanogaster

Hiroshi Ishimoto, Arianna Lark and Toshihiro Kitamoto

Frontiers in neurology, Vol.3, pp.1-5

2012

DOI: 10.3389/fneur.2012.00024

PMCID: PMC3286790

PMID: 22375135

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https://doi.org/10.3389/fneur.2012.00024View

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Abstract

Rest in the fruit fly Drosophila melanogaster has key characteristics of mammalian sleep and is thus considered as a fly version of sleep. Drosophila sleep has been studied extensively, with the aim of gaining fundamental insights into the evolutionarily conserved functions of sleep as well as the mechanisms that regulate it. An interesting question that has not yet been addressed is whether fly sleep can be classified into distinct sleep types, each having particular biological roles – like rapid eye movement (REM) and non-REM sleep in birds and mammals. Typically, Drosophila sleep displays a bimodal pattern, consisting of distinct daytime and nighttime components. Notably, daytime and nighttime sleep differ with respect to several qualities, such as sleep-bout lengths and arousal thresholds. In this short review, we describe several genetic and environmental factors that differentially affect daytime and nighttime sleep, highlighting the observations suggesting the notion that these temporally distinct components of Drosophila sleep may have unique biological functions and be regulated by different homeostatic regulatory mechanisms.

Neuroscience

sex peptide

ecdysone

angiotensin-converting enzyme-related gene

sleep stage

daytime and nighttime sleep

Drosophila melanogaster

Details

Title: Subtitle: Factors that Differentially Affect Daytime and Nighttime Sleep in Drosophila melanogaster
Creators: Hiroshi Ishimoto - Department of Anesthesia, Carver College of Medicine, University of Iowa
Arianna Lark - Interdisciplinary Graduate Program in Neuroscience, University of Iowa
Toshihiro Kitamoto - Department of Anesthesia, Carver College of Medicine, University of Iowa
Resource Type: Journal article
Publication Details: Frontiers in neurology, Vol.3, pp.1-5
DOI: 10.3389/fneur.2012.00024
PMID: 22375135
PMCID: PMC3286790
NLM abbreviation: Front Neurol
ISSN: 1664-2295
eISSN: 1664-2295
Publisher: Frontiers Research Foundation
Language: English
Date published: 2012
Academic Unit: Iowa Neuroscience Institute; Anesthesia; Neuroscience and Pharmacology
Record Identifier: 9984006364302771

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