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Failure of a Single Varicella Vaccination to Protect Children With Cancer From Life-Threatening Breakthrough Varicella
Journal article   Open access   Peer reviewed

Failure of a Single Varicella Vaccination to Protect Children With Cancer From Life-Threatening Breakthrough Varicella

James Kelley, Debra Tristram, Masaki Yamada and Charles Grose
The Pediatric infectious disease journal, Vol.34(9), pp.1027-1029
09/2015
DOI: 10.1097/INF.0000000000000737
PMCID: PMC4532322
PMID: 25955833
url
https://doi.org/10.1097/INF.0000000000000737View
Published (Version of record) Open Access

Abstract

We report 2 children with life-threatening breakthrough varicella. Both had received 1 varicella vaccination before onset of cancer. Despite treatment with intravenous acyclovir, 1 child died of disseminated varicella. Because similar fatal cases have been reported, high-risk immunocompromised children with 1 varicella vaccination may warrant the same varicella prophylaxis as immunocompromised children who have never been vaccinated.
varicella vaccine Brief Reports acyclovir varicella deaths

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