Journal article
Failure to learn from repeated mistakes: persistent decision-making impairment as measured by the iowa gambling task in patients with ventromedial prefrontal cortex lesions
Journal of the International Neuropsychological Society, Vol.18(5), pp.927-930
09/2012
DOI: 10.1017/S135561771200063X
PMID: 22643119
Abstract
Although frontal patients show impaired decision-making on the Iowa Gambling Task (IGT), there has been no follow-up study to date to determine whether there is recovery of function over time. We examined neurological participants' performance on repeated administrations of the IGT over the course of 6 years. We found that, while non-neurological participants showed considerable improvement due to practice effects on the IGT, patients with ventromedial prefrontal cortex (VMPFC) damage persisted in showing impaired performance on each retest. These results validate the clinical observations that VMPFC dysfunction does not appear to be subject to autonomous recovery over time in real-life. (JINS, 2012, 18, 1-4).
Details
- Title: Subtitle
- Failure to learn from repeated mistakes: persistent decision-making impairment as measured by the iowa gambling task in patients with ventromedial prefrontal cortex lesions
- Creators
- Samantha M Waters-Wood - Department of Psychology, University of Southern California, Los Angeles, California 90089-2520, USA. samantha.waters@usc.eduLin XiaoNatalie L DenburgMichael HernandezAntoine Bechara
- Resource Type
- Journal article
- Publication Details
- Journal of the International Neuropsychological Society, Vol.18(5), pp.927-930
- Publisher
- England
- DOI
- 10.1017/S135561771200063X
- PMID
- 22643119
- ISSN
- 1355-6177
- eISSN
- 1469-7661
- Grant note
- P50 NS019632 / NINDS NIH HHS R01 DA023051 / NIDA NIH HHS
- Language
- English
- Date published
- 09/2012
- Academic Unit
- Neurology; Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984070413902771
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