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False-positive pregnancy test associated with gonadoblastoma
Journal article   Open access   Peer reviewed

False-positive pregnancy test associated with gonadoblastoma

Francis J Schanne, Christopher S Cooper and Douglas A Canning
Urology (Ridgewood, N.J.), Vol.54(1), pp.162-162
1999
DOI: 10.1016/S0090-4295(98)00667-0
PMID: 10754126
url
https://doi.org/10.1016/S0090-4295(98)00667-0View
Published (Version of record) Open Access

Abstract

Gonadoblastomas are known to be hormonally active tumors that occur in streak or dysgenetic gonads of patients with intersex abnormalities. Several reports document their ability to produce beta-human chorionic gonadotropin (HCG), but none have documented an elevated peripheral serum beta-HCG. We report on the case of a patient with pure gonadal dysgenesis with XY karyotype who was found to have an elevated peripheral serum beta-HCG after a positive pregnancy test. Knowledge of gonadoblastoma’s potential to elevate serum beta-HCG levels may prevent unnecessary searches for other causes.

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