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Familial laryngeal paralysis
Journal article   Peer reviewed

Familial laryngeal paralysis

Jose M Manaligod and Richard J. H Smith
American journal of medical genetics, Vol.77(4), pp.277-280
05/26/1998
DOI: 10.1002/(SICI)1096-8628(19980526)77:4<277::AID-AJMG5>3.0.CO;2-K
PMID: 9600735

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Abstract

Vocal fold paralysis (VFP) is the second most frequent cause of congenital stridor. Although often due to birth trauma, infection, and brainstem abnormalities, most cases are idiopathic. Infrequently, a family history of VFP is elicited, identifying a role for genetic factors in laryngeal function. This study describes a family in which an autosomal dominant form of familial laryngeal abductor paralysis segregates. The typical physical findings, diagnostic and therpeutic considerations, and possible molecular mechanisms of this disorder are discussed in detail. Am. J. Med. Genet. 77:277–280, 1998. © 1998 Wiley‐Liss, Inc.
nucleus ambiguus vocal fold paralysis stridor

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