Journal article
Fear and panic in humans with bilateral amygdala damage
Nature neuroscience, Vol.16(3), pp.270-272
03/2013
DOI: 10.1038/nn.3323
PMCID: PMC3739474
PMID: 23377128
Abstract
Decades of research have highlighted the amygdala’s influential role in fear. Surprisingly, we found that inhalation of 35% CO
2
evoked not only fear, but also panic attacks, in three rare patients with bilateral amygdala damage. These results indicate that the amygdala is not required for fear and panic, and make an important distinction between fear triggered by external threats from the environment versus fear triggered internally by CO
2
.
Details
- Title: Subtitle
- Fear and panic in humans with bilateral amygdala damage
- Creators
- Justin S Feinstein - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USAColin Buzza - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USARene Hurlemann - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USARobin L Follmer - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USANader S Dahdaleh - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USAWilliam H Coryell - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USAMichael J Welsh - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USADaniel Tranel - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USAJohn A Wemmie - Department of Veterans Affairs Medical Center, Iowa City, Iowa, USA
- Resource Type
- Journal article
- Publication Details
- Nature neuroscience, Vol.16(3), pp.270-272
- DOI
- 10.1038/nn.3323
- PMID
- 23377128
- PMCID
- PMC3739474
- NLM abbreviation
- Nat Neurosci
- ISSN
- 1097-6256
- eISSN
- 1546-1726
- Language
- English
- Date published
- 03/2013
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute; Neurosurgery; Internal Medicine
- Record Identifier
- 9984001106602771
Metrics
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