Journal article
Feasibility and acceptability of Menopausia, Salud, Corazón (Menopause, Health, Heart): a pilot randomized trial to reduce cardiovascular disease risk in midlife Latinas
Menopause (New York, N.Y.), Vol.33(6), pp.641-652
06/2026
DOI: 10.1097/GME.0000000000002718
PMID: 41632258
Abstract
To evaluate the feasibility and acceptability of a multicomponent intervention to reduce cardiovascular disease (CVD) risk in perimenopausal Latinas.
Forty-nine perimenopausal Latinas (age 40-60 y) who spoke Spanish or English were randomized to a multicomponent intervention or waitlist control group. The intervention consisted of 12 weekly sessions (diet education, exercise, and stress management), followed by 3 months of continued support, and 6 months of independent skill maintenance. The primary outcomes were feasibility and acceptability measures, including enrollment and retention rates, intervention attendance, and intervention fidelity. Secondary outcomes included changes in CVD risk factors (eg, anthropometric measures, health behaviors, perceived stress, lipids, glucose, and arterial stiffness) from baseline to 6- and 12-month follow-up. Descriptive statistics, t tests, and χ2 were used to examine participant characteristics and changes in CVD risk factors.
Twenty-six women were randomly assigned to the intervention group and 23 to the waitlist control, who received the intervention after study completion. The mean age of the participants (n=49) was 47.1 ± 4.5 years, 98% were born outside of the United States, and 61% reported financial strain. Women attended an average of eight (53.3%) intervention sessions, with seven participants (26.7%) attending ≥80% of the intervention sessions. Forty-three participants (87.8%) completed the 6-month assessment, and 79.6% returned for 12-month data collection. At 12 months, 94.6% of participants would recommend the study to a friend or relative.
This pilot study found that a culturally tailored intervention consisting of diet education, exercise, and stress management may be feasible and acceptable to reduce CVD risk in perimenopausal Latinas.
Details
- Title: Subtitle
- Feasibility and acceptability of Menopausia, Salud, Corazón (Menopause, Health, Heart): a pilot randomized trial to reduce cardiovascular disease risk in midlife Latinas
- Creators
- Yamnia I Cortés - University of IowaLatesha K Harris - University of North Carolina at Chapel HillAndrea Cazales - University of North Carolina at Chapel HillValentina Marginean - East Carolina UniversityChristian Long - University of North Carolina at Chapel HillCheryl L Woods-Giscombé - University of North Carolina at Chapel HillKrista M Perreira - University of North Carolina at Chapel Hill
- Resource Type
- Journal article
- Publication Details
- Menopause (New York, N.Y.), Vol.33(6), pp.641-652
- DOI
- 10.1097/GME.0000000000002718
- PMID
- 41632258
- NLM abbreviation
- Menopause
- ISSN
- 1530-0374
- eISSN
- 1530-0374
- Publisher
- Lippincott; PHILADELPHIA
- Grant note
- National Institute of Nursing Research: T32NR007091 National Heart, Lung, and Blood Institute: K23MD014767 National Center for Complementary and Integrative Health: T32AT003378 National Institute on Minority Health and Health Disparities: R01MD015388
The authors sincerely thank the women who participated in this study for generously sharing their time. They are also grateful to those who volunteered and assisted with data collection, including Dr Mayra Duran, Lymari Casillas Santiago, and Margarita Mislan Diaz.
- Language
- English
- Electronic publication date
- 02/03/2026
- Date published
- 06/2026
- Academic Unit
- Nursing
- Record Identifier
- 9985139309302771
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