Journal article
Feasibility and optimization of ultra-short echo time MRI for improved imaging of IVC-filters at 3.0 T
Abdominal radiology (New York), Vol.46(1), pp.362-372
01/01/2021
DOI: 10.1007/s00261-020-02548-w
PMCID: PMC8167878
PMID: 32535691
Abstract
Purpose To determine the feasibility of ultra-short echo time (UTE) MRA for assessment of inferior vena cava (IVC) filters and evaluate the impact of different imaging protocols at 3.0 T, using conventional Cartesian MRA (cMRA) as the reference standard. Methods Patients with IVC-filters were recruited for this prospective IRB-approved, HIPAA-compliant study. Subjects underwent contrast-enhanced breath-held and a free-breathing 3D radial acquisition UTE-MRA (bhUTE, fbUTE) at three different flip angles (FA: 10 degrees, 15 degrees, 20 degrees) to optimize T1-weighted image quality. Two radiologists performed a direct comparison consensus reading to assess the optimal FA. Image quality (IQ) of both UTE techniques at the best FA was rated independently on a 4-point Likert scale (0 = non-diagnostic, 3 = excellent) and compared to 3D T1-weighted breath-held cMRA. Results Nine subjects were recruited. Low FAs of 10 degrees were rated best for both UTE techniques. fbUTE was excellent (3, IQR: 2; 3) and significantly better for IVC-filter depiction than cMRA (2, IQR: 0.75; 2, p = 0.001) and bhUTE (1.5, IQR: 0.75; 2, p < 0.001). Both UTE techniques showed significantly less filter-related artifacts (fbUTE: 28%, bhUTE: 33%) than cMRA (89%, p = 0.001 and p = 0.002, respectively). However, IQ of bhUTE was generally degraded due to high image noise and low image contrast. IQ of the IVC venogram was best with cMRA. Clinically relevant signal voids were only observed with the cage-shaped OptEase filter. Conclusion UTE-MRA is feasible at 3.0 T for the assessment of IVC-filters, particularly using a free-breathing protocol. Larger studies are needed to investigate the clinical utility of free-breathing UTE-MRA for assessment of IVC-filter-related complications.
Details
- Title: Subtitle
- Feasibility and optimization of ultra-short echo time MRI for improved imaging of IVC-filters at 3.0 T
- Creators
- Gesine Knobloch - University of Wisconsin–MadisonScott Nagle - University of Wisconsin–MadisonTimothy Colgan - University of Wisconsin–MadisonTilman Schubert - University of Wisconsin–MadisonKevin M. Johnson - University of Wisconsin–MadisonPeter Bannas - University of Wisconsin–MadisonGeng Li - University of Wisconsin–MadisonLouis Hinshaw - University of Wisconsin–MadisonJames Holmes - University of Wisconsin–MadisonScott B. Reeder - University of Wisconsin–Madison
- Resource Type
- Journal article
- Publication Details
- Abdominal radiology (New York), Vol.46(1), pp.362-372
- DOI
- 10.1007/s00261-020-02548-w
- PMID
- 32535691
- PMCID
- PMC8167878
- NLM abbreviation
- Abdom Radiol (NY)
- ISSN
- 2366-004X
- eISSN
- 2366-0058
- Publisher
- Springer Nature
- Number of pages
- 11
- Grant note
- Wisconsin Alumni Research Foundation General Electrics Healthcare K24 DK102595; T32CA009206 / National Institute of Health (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Departments of Radiology and Medical Physics at the University of Wisconsin Bracco Diagnostics University of Wisconsin-Madison Office of the Vice Chancellor for Research and Graduate Education
- Language
- English
- Date published
- 01/01/2021
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology
- Record Identifier
- 9984294926002771
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