Feasibility of prolonged continuous glucose monitoring in toddlers with type 1 diabetes

Eva Tsalikian; Larry Fox; Stuart Weinzimer; Bruce Buckingham; Neil H White; Roy Beck; Craig Kollman; Dongyuan Xing; Katrina Ruedy; Diabetes Research in Children Network Study Group

doi:10.1111/j.1399-5448.2011.00837.x

Back

Feasibility of prolonged continuous glucose monitoring in toddlers with type 1 diabetes

Journal article

Peer reviewed

Feasibility of prolonged continuous glucose monitoring in toddlers with type 1 diabetes

Eva Tsalikian, Larry Fox, Stuart Weinzimer, Bruce Buckingham, Neil H White, Roy Beck, Craig Kollman, Dongyuan Xing, Katrina Ruedy and Diabetes Research in Children Network Study Group

Pediatric diabetes, Vol.13(4), pp.301-307

06/2012

DOI: 10.1111/j.1399-5448.2011.00837.x

PMCID: PMC3665108

PMID: 22151826

Files and links (1)

url

https://www.ncbi.nlm.nih.gov/pmc/articles/3665108View

Open Access

Abstract

To examine the feasibility of continuous glucose monitoring (CGM) use in very young children with type 1 diabetes (T1D). Twenty-three children less than 4 yr of age with T1D were provided with a FreeStyle Navigator(®) (n = 21) or a Paradigm(®) (n = 2) CGM device. At baseline, mean age was 3.0 ± 0.8 yr, mean hemoglobin A1c (HbA1c) was 8.0 ± 0.8%, 10 were using an insulin pump and 13 were on multiple daily injections. CGM use was evaluated over a 6-month period. Three children dropped out of the study before the end of 6 months. Among the 20 children who completed 6 months of follow-up, CGM use in month 6 was ≥6 d/wk in 9 (45%), 4 ≤ 6 d/wk in 2 (10%), and <4 d/wk in 9 (45%). Skin reactions were minimal. Although there was no detectable change in mean HbA1c between baseline and 6 months (7.9 and 8.0%, respectively), there was a high degree of parental satisfaction with CGM as measured on the CGM satisfaction scale questionnaire. A high percentage of glucose values were in the hyperglycemic range, and biochemical hypoglycemia was infrequent. More than 40% of very young children were able to safely use CGM on a near-daily basis after 6 months. CGM demonstrated frequent hyperglycemic excursions, with a large variability in glucose readings. Although improvement in glycemic control was not detected in the group as a whole, parental satisfaction with CGM was high.

Diabetes Mellitus, Type 1 - physiopathology

Glycated Hemoglobin A - metabolism

Humans

Parents

Child, Preschool

Infant

Male

Diabetes Mellitus, Type 1 - drug therapy

Feasibility Studies

Patient Satisfaction

Hypoglycemia - prevention & control

Blood Glucose Self-Monitoring

Female

Blood Glucose - metabolism

Details

Title: Subtitle: Feasibility of prolonged continuous glucose monitoring in toddlers with type 1 diabetes
Creators: Eva Tsalikian - Pediatric Endocrinology and Diabetes, University of Iowa, Iowa City, IA 52242, USA. direcnet@jaeb.org
Larry Fox
Stuart Weinzimer
Bruce Buckingham
Neil H White
Roy Beck
Craig Kollman
Dongyuan Xing
Katrina Ruedy
Diabetes Research in Children Network Study Group
Resource Type: Journal article
Publication Details: Pediatric diabetes, Vol.13(4), pp.301-307
DOI: 10.1111/j.1399-5448.2011.00837.x
PMID: 22151826
PMCID: PMC3665108
NLM abbreviation: Pediatr Diabetes
ISSN: 1399-543X
eISSN: 1399-5448
Grant note: U10 HD041890 / NICHD NIH HHS HD41890-10 / NICHD NIH HHS U10 HD041906 / NICHD NIH HHS U10 HD041918 / NICHD NIH HHS HD56526 / NICHD NIH HHS K12 DK094714 / NIDDK NIH HHS U10 HD041915 / NICHD NIH HHS HD41918 / NICHD NIH HHS HD41908-10 / NICHD NIH HHS HD41906-10 / NICHD NIH HHS U10 HD041908 / NICHD NIH HHS HD41915 / NICHD NIH HHS U10 HD056526 / NICHD NIH HHS U01 HD041890 / NICHD NIH HHS
Language: English
Date published: 06/2012
Academic Unit: Stead Family Department of Pediatrics; Fraternal Order of Eagles Diabetes Research Center
Record Identifier: 9984093340902771

Metrics

20 Record Views

63 Times Cited - Web of Science