Features versus Feelings: Dissociable Representations of the Acoustic Features and Valence of Aversive Sounds

Sukhbinder Kumar; Katharina von Kriegstein; Karl Friston; Timothy D. Griffiths

doi:10.1523/JNEUROSCI.1759-12.2012

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Features versus Feelings: Dissociable Representations of the Acoustic Features and Valence of Aversive Sounds

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Features versus Feelings: Dissociable Representations of the Acoustic Features and Valence of Aversive Sounds

Sukhbinder Kumar, Katharina von Kriegstein, Karl Friston and Timothy D. Griffiths

The Journal of neuroscience, Vol.32(41), pp.14184-14192

10/10/2012

DOI: 10.1523/JNEUROSCI.1759-12.2012

PMCID: PMC3505833

PMID: 23055488

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Abstract

This study addresses the neuronal representation of aversive sounds that are perceived as unpleasant. Functional magnetic resonance imaging in humans demonstrated responses in the amygdala and auditory cortex to aversive sounds. We show that the amygdala encodes both the acoustic features of a stimulus and its valence (perceived unpleasantness). Dynamic causal modeling of this system revealed that evoked responses to sounds are relayed to the amygdala via auditory cortex. While acoustic features modulate effective connectivity from auditory cortex to the amygdala, the valence modulates the effective connectivity from amygdala to the auditory cortex. These results support a complex (recurrent) interaction between the auditory cortex and amygdala based on object-level analysis in the auditory cortex that portends the assignment of emotional valence in amygdala that in turn influences the representation of salient information in auditory cortex.

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

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Details

Title: Subtitle: Features versus Feelings: Dissociable Representations of the Acoustic Features and Valence of Aversive Sounds
Creators: Sukhbinder Kumar - Newcastle University
Katharina von Kriegstein - Max Planck Society
Karl Friston - Newcastle University
Timothy D. Griffiths - Newcastle University
Resource Type: Journal article
Publication Details: The Journal of neuroscience, Vol.32(41), pp.14184-14192
DOI: 10.1523/JNEUROSCI.1759-12.2012
PMID: 23055488
PMCID: PMC3505833
NLM abbreviation: J Neurosci
ISSN: 0270-6474
eISSN: 1529-2401
Publisher: Soc Neuroscience
Number of pages: 9
Grant note: Wellcome Trust; European Commission
Language: English
Date published: 10/10/2012
Academic Unit: Psychological and Brain Sciences; Neurosurgery
Record Identifier: 9984303904102771

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