Journal article
Fecal Fingerprints of Enteric Pathogen Contamination in Public Environments of Kisumu, Kenya, Associated with Human Sanitation Conditions and Domestic Animals
Environmental science & technology, Vol.52(18), pp.10263-10274
09/18/2018
DOI: 10.1021/acs.est.8b01528
PMCID: PMC6557411
PMID: 30106283
Abstract
Young children are infected by a diverse range of enteric pathogens in high disease burden settings, suggesting pathogen contamination of the environment is equally diverse. This study aimed to characterize across- and within-neighborhood diversity in enteric pathogen contamination of public domains in urban informal settlements of Kisumu, Kenya, and to assess the relationship between pathogen detection patterns and human and domestic animal sanitation conditions. Microbial contamination of soil and surface water from 166 public sites in three Kisumu neighborhoods was measured by enterococcal assays and quantitative reverse transcription polymerase chain reaction (qRT-PCR) for 19 enteric pathogens. Regression was used to assess the association between observed sanitary indicators of contamination with enterococci and pathogen presence and concentration, and pathogen diversity. Seventeen types of pathogens were detected in Kisumu public domains. Enteric pathogens were codetected in 33% of soil and 65% of surface water samples. Greater pathogen diversity was associated with the presence of domestic animal feces but not with human open defecation, deteriorating latrines, flies, or disposal of human feces. Sanitary conditions were not associated with enterococcal bacteria, specific pathogen concentrations, or “any pathogen”. Young children played at 40% of observed sites. Managing domestic animal feces may be required to reduce enteric pathogen environmental contamination in high-burden settings.
Details
- Title: Subtitle
- Fecal Fingerprints of Enteric Pathogen Contamination in Public Environments of Kisumu, Kenya, Associated with Human Sanitation Conditions and Domestic Animals
- Creators
- Kelly K Baker - Department of Occupational and Environmental HealthReid Senesac - Department of Occupational and Environmental HealthDaniel Sewell - Department of BiostatisticsAnanya Sen Gupta - University of IowaOliver Cumming - University of LondonJane Mumma - Great Lakes University of Kisumu
- Resource Type
- Journal article
- Publication Details
- Environmental science & technology, Vol.52(18), pp.10263-10274
- DOI
- 10.1021/acs.est.8b01528
- PMID
- 30106283
- PMCID
- PMC6557411
- NLM abbreviation
- Environ Sci Technol
- ISSN
- 0013-936X
- eISSN
- 1520-5851
- Grant note
- DOI: 10.13039/100000066, name: National Institute of Environmental Health Sciences, award: P30 ES005605; DOI: 10.13039/100008893, name: University of Iowa
- Language
- English
- Date published
- 09/18/2018
- Academic Unit
- Electrical and Computer Engineering; Occupational and Environmental Health; Epidemiology; Biostatistics; Public Policy Center (Archive)
- Record Identifier
- 9984196973202771
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