Journal article
Feminizing chicks: a model for avian sex determination based on titration of Hint enzyme activity and the predicted structure of an Asw-Hint heterodimer
Genome Biology, Vol.4(3), pp.R18-R18
2003
DOI: 10.1186/gb-2003-4-3-r18
PMID: 12620103
Abstract
In birds females are heterogametic with a ZW karyotype, while males are ZZ homogametes but the molecular basis for sexual differentiation in birds is unknown. Genomic and expression data suggest that Asw may feminize chicks, dominantly interfering with Hint function by heterodimerization.
Details
- Title: Subtitle
- Feminizing chicks: a model for avian sex determination based on titration of Hint enzyme activity and the predicted structure of an Asw-Hint heterodimer
- Creators
- Helen C Pace - Correspondence: Charles Brenner. E-mail: brenner@dada.jci.tju.eduCharles Brenner - Correspondence: Charles Brenner. E-mail: brenner@dada.jci.tju.edu
- Resource Type
- Journal article
- Publication Details
- Genome Biology, Vol.4(3), pp.R18-R18
- DOI
- 10.1186/gb-2003-4-3-r18
- PMID
- 12620103
- NLM abbreviation
- Genome Biol
- ISSN
- 1474-7596
- eISSN
- 1474-760X
- Publisher
- BioMed Central; London
- Copyright
- © 2003 Pace and Brenner; licensee BioMed Central Ltd.
- Language
- English
- Date published
- 2003
- Academic Unit
- Biochemistry and Molecular Biology; Internal Medicine
- Record Identifier
- 9983788596902771
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