Journal article
Fetal alcohol syndrome: Craniofacial and central nervous system manifestations
American journal of medical genetics, Vol.61(4), pp.329-339
02/02/1996
DOI: 10.1002/(SICI)1096-8628(19960202)61:4<329::AID-AJMG6>3.0.CO;2-P
PMID: 8834044
Abstract
Magnetic resonance imaging (MRI) is undertaken on fetal alcohol syndrome (FAS) subjects to document central nervous system (CNS) anomalies. The abnormalities found include agenesis and hypoplasia of the corpus callosum, cavum septi pellucidi, cavum vergae, ventriculomegaly, hypoplasia of inferior olivary eminences, small brain stem, and micrencephaly. Craniofacial anomalies range from the well‐recognized FAS physiognomy to the more severe frontonasal “dysplasia” (median cleft face). CNS and craniofacial abnormalities are predominantly symmetric and central or midline. The association of these anomalies becomes self‐evident with recognition of the concept of the midline as a special developmental field, vulnerable to adverse factors during embryogenesis and fetal growth and development. © 1996 Wiley‐Liss, Inc.
Details
- Title: Subtitle
- Fetal alcohol syndrome: Craniofacial and central nervous system manifestations
- Creators
- Virginia P JohnsonVictor W SwayzeYutaka SatoNancy C Andreasen
- Resource Type
- Journal article
- Publication Details
- American journal of medical genetics, Vol.61(4), pp.329-339
- DOI
- 10.1002/(SICI)1096-8628(19960202)61:4<329::AID-AJMG6>3.0.CO;2-P
- PMID
- 8834044
- NLM abbreviation
- Am J Med Genet
- ISSN
- 0148-7299
- eISSN
- 1096-8628
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company; New York
- Number of pages
- 11
- Language
- English
- Date published
- 02/02/1996
- Academic Unit
- Radiology; Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003408802771
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