Journal article
Fine motor skills in adult Tourette patients are task-dependent
BMC neurology, Vol.12(1), pp.120-120
10/11/2012
DOI: 10.1186/1471-2377-12-120
PMID: 23057645
Abstract
Background
Tourette syndrome is a neuropsychiatric disorder characterized by motor and phonic tics. Deficient motor inhibition underlying tics is one of the main hypotheses in its pathophysiology. Therefore the question arises whether this supposed deficient motor inhibition affects also voluntary movements. Despite severe motor tics, different personalities who suffer from Tourette perform successfully as neurosurgeon, pilot or professional basketball player.
Methods
For the investigation of fine motor skills we conducted a motor performance test battery in an adult Tourette sample and an age matched group of healthy controls.
Results
The Tourette patients showed a significant lower performance in the categories steadiness of both hands and aiming of the right hand in comparison to the healthy controls. A comparison of patients’ subgroup without comorbidities or medication and healthy controls revealed a significant difference in the category steadiness of the right hand.
Conclusions
Our results show that steadiness and visuomotor integration of fine motor skills are altered in our adult sample but not precision and speed of movements. This alteration pattern might be the clinical vignette of complex adaptations in the excitability of the motor system on the basis of altered cortical and subcortical components. The structurally and functionally altered neuronal components could encompass orbitofrontal, ventrolateral prefrontal and parietal cortices, the anterior cingulate, amygdala, primary motor and sensorimotor areas including altered corticospinal projections, the corpus callosum and the basal ganglia.
Details
- Title: Subtitle
- Fine motor skills in adult Tourette patients are task-dependent
- Creators
- Irene Neuner - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, GermanyJorge Arrubla - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, GermanyCorinna Ehlen - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, GermanyHildegard Janouschek - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, GermanyCarlos Nordt - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, GermanyBruno Fimm - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, GermanyFrank Schneider - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, GermanyN Jon Shah - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, GermanyWolfram Kawohl - Department of Psychiatry Psychotherapy and Psychosomatics, RWTH Aachen University, Pauwelsstrasse 30, Aachen, 52074, Germany
- Resource Type
- Journal article
- Publication Details
- BMC neurology, Vol.12(1), pp.120-120
- DOI
- 10.1186/1471-2377-12-120
- PMID
- 23057645
- NLM abbreviation
- BMC Neurol
- ISSN
- 1471-2377
- eISSN
- 1471-2377
- Publisher
- BioMed Central
- Language
- English
- Date published
- 10/11/2012
- Academic Unit
- Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003972702771
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