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Fine‐needle aspiration biopsy of subcutaneous fat necrosis of the newborn
Journal article   Peer reviewed

Fine‐needle aspiration biopsy of subcutaneous fat necrosis of the newborn

William P Walker, Richard J. H Smith and Michael B Cohen
Diagnostic cytopathology, Vol.9(3), pp.329-332
05/1993
DOI: 10.1002/dc.2840090318
PMID: 8519201

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Abstract

This report provides the first description of the fine‐needle aspiration biopsy findings in a case of subcutaneous fat necrosis of the newborn. While initial interpretation of the aspirate smears was suspicious for a neoplastic process, subsequent incisional biopsy confirmed the benign nature of the lesion. Review of the cytologic material revealed rare, negatively stained, needle‐shaped crystals within histiocytes and multinucleate giant cells. In the appropriate clinical setting, and given a mixture of lymphocytes, histiocytes, and multinucleate giant cells in the aspirate smears, we believe the finding of negatively stained needle‐shaped crystals can strongly suggest the diagnosis of subcutaneous fat necrosis of the newborn.
FNAB Soft tissue Histiocyte Pediatric Crystals

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