Journal article
Fish intake and the risk of incident heart failure: the Women's Health Initiative
Circulation. Heart failure, Vol.4(4), pp.404-413
07/2011
DOI: 10.1161/CIRCHEARTFAILURE.110.960450
PMCID: PMC3310223
PMID: 21610249
Abstract
Whether fish or the fatty acids they contain are independently associated with risk for incident heart failure (HF) among postmenopausal women is unclear.
The baseline Women's Health Initiative Observational Study cohort consisted of 93 676 women ages 50 to 79 years of diverse ethnicity and background, of which 84 493 were eligible for analyses. Intakes of baked/broiled fish, fried fish, and omega-3 fatty acid (eicosapentaenoic acid+docosahexaenoic acid, α-linolenic acid), and trans-fatty acid were determined from the Women's Health Initiative food frequency questionnaire. Baked/broiled fish consumption was divided into 5 frequency categories: <1/mo (referent), 1 to 3/mo, 1 to 2/wk, 3 to 4/wk, ≥5/wk. Fried fish intake was grouped into 3 frequency categories: <1/mo (referent), 1-3/mo, and ≥1/wk. Associations between fish or fatty acid intake and incident HF were determined using Cox models adjusting for HF risk factors and dietary factors. Baked/broiled fish consumption (≥5 servings/wk at baseline) was associated with a hazard ratio of 0.70 (95% confidence interval, 0.51 to 0.95) for incident HF. In contrast, fried fish consumption (≥1 serving/wk at baseline) was associated with a hazard ratio of 1.48 (95% confidence interval, 1.19 to 1.84) for incident HF. No significant associations were found between eicosapentaenoic acid+docosahexaenoic acid, α-linolenic acid, or trans-fatty acid intake and incident HF.
Increased baked/broiled fish intake may lower HF risk, whereas increased fried fish intake may increase HF risk in postmenopausal women.
Details
- Title: Subtitle
- Fish intake and the risk of incident heart failure: the Women's Health Initiative
- Creators
- Rashad J Belin - Northwestern UniversityPhilip Greenland - Preventive MedicineLisa Martin - George Washington UniversityAlbert Oberman - University of Alabama at BirminghamLesley Tinker - Women's Health InitiativeJennifer RobinsonJoseph Larson - Women's Health InitiativeLinda Van Horn - Preventive MedicineDonald Lloyd-Jones - Preventive Medicine
- Resource Type
- Journal article
- Publication Details
- Circulation. Heart failure, Vol.4(4), pp.404-413
- DOI
- 10.1161/CIRCHEARTFAILURE.110.960450
- PMID
- 21610249
- PMCID
- PMC3310223
- NLM abbreviation
- Circ Heart Fail
- ISSN
- 1941-3289
- eISSN
- 1941-3297
- Grant note
- N01WH42123 / WHI NIH HHS T32 HL069771-03 / NHLBI NIH HHS N01WH32111 / WHI NIH HHS UL1 RR025741 / NCRR NIH HHS N01WH42118 / WHI NIH HHS N01WH42114 / WHI NIH HHS N01WH42110 / WHI NIH HHS N01WH32106 / WHI NIH HHS N01WH32119 / WHI NIH HHS N01WH32115 / WHI NIH HHS N01WH32102 / WHI NIH HHS N01WH24152 / WHI NIH HHS N01WH32101 / WHI NIH HHS N01WH42108 / WHI NIH HHS N01WH4230 / WHI NIH HHS N01WH42126 / WHI NIH HHS N01WH42113 / WHI NIH HHS N01WH42117 / WHI NIH HHS N01WH44221 / WHI NIH HHS N01WH32109 / WHI NIH HHS N01WH32105 / WHI NIH HHS N01WH32118 / WHI NIH HHS N01WH42122 / WHI NIH HHS N01WH42107 / WHI NIH HHS N01WH4231 / WHI NIH HHS N01WH42125 / WHI NIH HHS N01WH42112 / WHI NIH HHS N01WH42129 / WHI NIH HHS N01WH32122 / WHI NIH HHS N01WH42116 / WHI NIH HHS N01WH32108 / WHI NIH HHS N01WH32113 / WHI NIH HHS N01 WH032108 / WHI NIH HHS N01WH32100 / WHI NIH HHS N01WH42121 / WHI NIH HHS N01WH42115 / WHI NIH HHS N01WH42124 / WHI NIH HHS N01WH32112 / WHI NIH HHS N01WH4232 / WHI NIH HHS N01WH42119 / WHI NIH HHS N01WH22110 / WHI NIH HHS N01WH42111 / WHI NIH HHS N01WH42120 / WHI NIH HHS N01WH42109 / WHI NIH HHS T32 HL069771 / NHLBI NIH HHS
- Language
- English
- Date published
- 07/2011
- Academic Unit
- Epidemiology; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984364403002771
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