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Flip-flop phenomenon in systemic sclerosis on fluorodeoxyglucose positron emission tomography/computed tomography
Journal article   Open access   Peer reviewed

Flip-flop phenomenon in systemic sclerosis on fluorodeoxyglucose positron emission tomography/computed tomography

Kevser Oksuzoglu, Gulsen Ozen, Sabahat Inanir and Rafi Haner Direskeneli
Indian journal of nuclear medicine, Vol.30(4), pp.350-351
10/01/2015
DOI: 10.4103/0972-3919.164018
PMCID: PMC4579625
PMID: 26430324
url
https://europepmc.org/articles/pmc4579625View
Published (Version of record) Open Access

Abstract

Systemic sclerosis (SSc) is a rare autoimmune disease, which may affect multiple organ systems. Fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) can demonstrate the degree and anatomical extent of involvement in the entire body and coexisting malignancies in connective tissue diseases. We present a case of SSc with an increased 18F-FDG uptake in the cutaneous and subcutaneous tissues even higher than the neighboring skeletal muscles ("flip-flop phenomenon," that is, an increased 18F-FDG uptake in the skin but a decreased 18F-FDG uptake in the skeletal muscles).
Life Sciences & Biomedicine Radiology, Nuclear Medicine & Medical Imaging Science & Technology

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