Flow-induced signal misallocation artifacts in two-point fat-water chemical shift MRI

Mahdi Salmani Rahimi; James H Holmes; Kang Wang; Scott B Reeder; Frank R Korosec

doi:10.1002/mrm.25315

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Flow-induced signal misallocation artifacts in two-point fat-water chemical shift MRI

Journal article

Open access

Peer reviewed

Flow-induced signal misallocation artifacts in two-point fat-water chemical shift MRI

Mahdi Salmani Rahimi, James H Holmes, Kang Wang, Scott B Reeder and Frank R Korosec

Magnetic resonance in medicine, Vol.73(5), pp.1926-1931

05/2015

DOI: 10.1002/mrm.25315

PMCID: PMC4363294

PMID: 24911325

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https://doi.org/10.1002/mrm.25315View

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Abstract

Two-point fat-water separation methods are increasingly being used for chest and abdominal MRI and have recently been introduced for use in MR angiography of the lower extremities. With these methods, flowing spins can accumulate unintended phase shifts between the echo times. The purpose of this study is to demonstrate that these phase shifts can lead to inaccurate signals in the water and fat images. In vitro experiments were conducted at 1.5T and 3.0T using a stenosis-mimicking phantom and a computer-controlled pump to image a range of physiologically relevant velocities. In the phantom images acquired using bipolar readout gradients, fat-water signal inaccuracies were visible in regions of flow, with increasing severity as the flow rate was increased. Additionally, similar effects were observed in regions of high flow in clinical chest and liver exams. In the phantom images, the effect was eliminated by using a dual-pass method without bipolar readout gradients. When using fat-water separation methods with bipolar readout gradients, phase shifts caused by the motion of spins can lead to signal inaccuracies in the fat and water images. These artifacts can be mitigated by using approaches that do not use bipolar readout gradients.

Adipose Tissue

Algorithms

Artifacts

Blood Flow Velocity - physiology

Body Water

Constriction, Pathologic - diagnosis

Constriction, Pathologic - physiopathology

Contrast Media

Equipment Design

Humans

Image Enhancement - methods

Image Interpretation, Computer-Assisted - methods

Imaging, Three-Dimensional - methods

Leg - blood supply

Magnetic Resonance Angiography - instrumentation

Magnetic Resonance Angiography - methods

Phantoms, Imaging

Sensitivity and Specificity

Signal-To-Noise Ratio

Vascular Diseases - diagnosis

Vascular Diseases - physiopathology

Details

Title: Subtitle: Flow-induced signal misallocation artifacts in two-point fat-water chemical shift MRI
Creators: Mahdi Salmani Rahimi - University of Wisconsin–Madison
James H Holmes - Global MR Applications & Workflow GE Healthcare Madison Wisconsin USA
Kang Wang - Global MR Applications & Workflow GE Healthcare Madison Wisconsin USA
Scott B Reeder - University of Wisconsin–Madison
Frank R Korosec - University of Wisconsin–Madison
Resource Type: Journal article
Publication Details: Magnetic resonance in medicine, Vol.73(5), pp.1926-1931
DOI: 10.1002/mrm.25315
PMID: 24911325
PMCID: PMC4363294
NLM abbreviation: Magn Reson Med
ISSN: 0740-3194
eISSN: 1522-2594
Grant note: R01 DK083380 / NIDDK NIH HHS R01 DK088925 / NIDDK NIH HHS
Language: English
Date published: 05/2015
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology
Record Identifier: 9984294923502771

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