Journal article
Follicular lymphomatoid papulosis with follicular mucinosis: a clinicopathologic study of 3 cases with literature review and conceptual reappraisal
Journal of cutaneous pathology, Vol.44(4), pp.360-366
04/2017
DOI: 10.1111/cup.12871
PMID: 28009441
Abstract
Lymphomatoid papulosis (LyP), characterized by recurring, waxing and waning, cutaneous papulonodules, is increasingly recognized to represent a heterogeneous collection of pathologically dissimilar subtypes. Recently, a follicular LyP variant was proposed, featuring folliculotropism. Folliculotropism by atypical lymphocytes is conventionally associated with follicular mucinosis and mycosis fungoides (MF), and review of the literature suggests co-occurrence of folliculotropism and follicular mucinosis in LyP to be rare, with only 3 cases identified to date. Herein we describe 3 additional cases, each manifesting a typical LyP clinical picture, with the additional element of folliculotropism and follicular mucinosis on pathology. These cases suggest that LyP should be considered alongside MF in the differential diagnosis of follicular mucinosis with accompanying atypical lymphocytic infiltration. As LyP can occur with other lymphoproliferative disorders such as MF, the finding of follicular mucinosis in LyP may further represent a conceptual intersection between the 2 disease processes.
Details
- Title: Subtitle
- Follicular lymphomatoid papulosis with follicular mucinosis: a clinicopathologic study of 3 cases with literature review and conceptual reappraisal
- Creators
- Emilie Dore - Department of Dermatology, University of Iowa, Iowa City, IowaBrian L Swick - Department of Dermatology and Pathology, University of Iowa, Iowa City, IowaBrian K Link - Department of Oncology, University of Iowa, Iowa City, IowaGrant K Ghahramani - Department of Dermatology, University of Iowa, Iowa City, IowaVincent Liu - Department of Dermatology and Pathology, University of Iowa, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of cutaneous pathology, Vol.44(4), pp.360-366
- Publisher
- United States
- DOI
- 10.1111/cup.12871
- PMID
- 28009441
- ISSN
- 0303-6987
- eISSN
- 1600-0560
- Grant note
- P30 CA030199 / NCI NIH HHS P30 CA086862 / NCI NIH HHS
- Language
- English
- Date published
- 04/2017
- Academic Unit
- Dermatology; Hematology, Oncology, and Blood & Marrow Transplantation; Pathology; Internal Medicine
- Record Identifier
- 9984025370802771
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