Journal article
Follow-Up of Treatment of a Cerebral Arteriovenous Malformation With Acetazolamide and Positron Emission Tomography
Clinical nuclear medicine, Vol.20(7), pp.639-641
07/1995
DOI: 10.1097/00003072-199507000-00020
PMID: 7554674
Abstract
Cerebral arteriovenous malformations (AVM) may cause decreased perfusion (“steal”) to the surrounding brain tissue. Abrupt occlusion of the shunt has led to fulminant hyperemic catastrophes in some patients. The perfusion reserve of these areas has been previously evaluated with acetazolamide, a vasodilatory agent, using SPECT. Abnormal response to acetazolamide has been shown to correlate with intraoperative and postoperative complications. A 34-year-old man with seizures had a 3 cm x 4 cm AVM at the left occipitoparietal region. Quantitative brain blood flow studies were performed using 0–15 water and positron emission tomography (PET), before and immediately after the embolization, and 4 days later. These studies demonstrated no cerebral “steal” or abnormal response of the perilesional tissue to acetazolamide. Four weeks after the embolization the patient underwent surgical resection of the AVM with no complications and complete recovery. Cerebral blood flow measurements by either SPECT or PET are useful in the preoperative evaluation of patients with AVM.
Details
- Title: Subtitle
- Follow-Up of Treatment of a Cerebral Arteriovenous Malformation With Acetazolamide and Positron Emission Tomography
- Creators
- ESTHER ARGENYI - University of lowa Hospitals and Clinics, Department of Radiology, lowa City, lowaLAURA BOLES PONTORICHARD HICHWAG WATKINSPETER KIRCHNERTONY RYALS
- Resource Type
- Journal article
- Publication Details
- Clinical nuclear medicine, Vol.20(7), pp.639-641
- Publisher
- Lippincott-Raven Publishers
- DOI
- 10.1097/00003072-199507000-00020
- PMID
- 7554674
- ISSN
- 0363-9762
- eISSN
- 1536-0229
- Language
- English
- Date published
- 07/1995
- Academic Unit
- Radiology; Research Administration; Pharmaceutical Sciences and Experimental Therapeutics; Physics and Astronomy; Radiation Oncology
- Record Identifier
- 9984051894802771
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