Journal article
Forebrain Structure in Infantile Autism
Journal of the American Academy of Child and Adolescent Psychiatry, Vol.28(4), pp.534-537
07/1989
DOI: 10.1097/00004583-198907000-00011
PMID: 2768148
Abstract
Researchers implicate central nervous system dysfunction in infantile autism, but postmortem examinations and in vivo brain imaging studies have produced conflicting results concerning the neuronal systems involved. Magnetic resonance imaging—a new modality of in vivo brain imaging—was used to investigate the cerebral and thalamic structure of 105 autistic patients. Compared with the control group, there was an overall difference in the forebrain morphology of the autistic subjects due to subtle but statistically significant differences in the anterior ventricular horns, lateral ventricles, and the right lenticular nucleus. These results, when considered with previous studies of cerebral structure, suggest that there are subtle alterations in the forebrain of autistic patients.
Details
- Title: Subtitle
- Forebrain Structure in Infantile Autism
- Creators
- GARY R GAFFNEYSAMUEL KUPERMANLUKE Y TSAISUSAN MINCHIN
- Resource Type
- Journal article
- Publication Details
- Journal of the American Academy of Child and Adolescent Psychiatry, Vol.28(4), pp.534-537
- DOI
- 10.1097/00004583-198907000-00011
- PMID
- 2768148
- NLM abbreviation
- J Am Acad Child Adolesc Psychiatry
- ISSN
- 0890-8567
- eISSN
- 1527-5418
- Publisher
- Elsevier Inc
- Grant note
- MH-39437 / NIMH
- Language
- English
- Date published
- 07/1989
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics
- Record Identifier
- 9984004181602771
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