Journal article
From Gestational Hypertension and Preeclampsia to Atypical Hemolytic Uremic Syndrome
Obstetrics and gynecology (New York. 1953), Vol.127(5), pp.907-910
05/2016
DOI: 10.1097/AOG.0000000000001340
PMID: 27054930
Abstract
Preeclampsia is a leading cause of morbidity and mortality during pregnancy. The variability of clinical features suggests that preeclampsia is not a single disease. Atypical hemolytic uremic syndrome, resulting from defective regulation of the alternative complement pathway, is less well known and may be mistaken for preeclampsia.
We describe a woman with atypical hemolytic uremic syndrome who was given the diagnosis of gestational hypertension during her first pregnancy and preeclampsia and hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome followed by thrombotic thrombocytopenic purpura and hemolytic uremic syndrome during her second pregnancy, before the correct diagnosis of atypical hemolytic uremic syndrome was recognized in the postpartum period of her third pregnancy. The patient was treated with anticomplement therapy and had a rapid improvement.
This case illustrates the importance of distinguishing atypical hemolytic uremic syndrome from preeclampsia.
Details
- Title: Subtitle
- From Gestational Hypertension and Preeclampsia to Atypical Hemolytic Uremic Syndrome
- Creators
- Han-Mou Tsai - iMAH Hematology Associates, New Hyde Park, New York; and the Division of Nephrology, University of Texas Southwestern School of Medicine, Dallas, TexasElizabeth Kuo
- Resource Type
- Journal article
- Publication Details
- Obstetrics and gynecology (New York. 1953), Vol.127(5), pp.907-910
- DOI
- 10.1097/AOG.0000000000001340
- PMID
- 27054930
- ISSN
- 0029-7844
- eISSN
- 1873-233X
- Language
- English
- Date published
- 05/2016
- Academic Unit
- Nephrology; Internal Medicine
- Record Identifier
- 9984094334602771
Metrics
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