Journal article
Frontal Behavioral Syndromes in Cortical and Subcortical Dementia
Assessment (Odessa, Fla.), Vol.3(3), pp.327-337
09/1996
DOI: 10.1177/1073191196003003012
Abstract
The Frontal Lobe Personality Scale (FLOPS; Grace & Malloy, 1992) was administered to the caregivers of 51 patients with neurodegenerative disease to examine personality and behavioral features associated with prototypical "cortical" dementia (i.e., Dementia of the Alzheimer Type; DAT) and "subcortical" dementia (i.e., Huntington's disease; HD). The FLOPS is a 45-item behavior rating scale designed to identify three frontal syndromes: (a) apathy, (b) disinhibition, and (c) executive dysfunction.
Comparing subgroups of HD and DAT that were matched for age and dementia severity (ns = 12), the HD subgroup had higher FLOPS apathy ratings. Using all patients, FLOPS ratings were associated with traditional neuropsychological measures as well as a measure of everyday functioning.
Discriminant function analyses, accurately classified over 92% of the DAT patients and nearly 77% of the HD patients, which is consistent with the discriminative utility of other traditional neuropsychological tests. These data suggest that informant-based ratings of so-called "frontal lobe" behaviors may be a useful adjunct to current neuropsychological evaluations in an attempt to characterize personality changes that co-occur with neurodegenerative disease.
Details
- Title: Subtitle
- Frontal Behavioral Syndromes in Cortical and Subcortical Dementia
- Creators
- Jane S. Paulsen - San Francisco VA Medical CenterJulie C. Stout - Indiana UniversityJody DeLaPena - University of California San DiegoRamon Romero - University of California San DiegoZeena Tawfik-Reedy - University of California San DiegoMichael R. Swenson - University of California San DiegoJanet Grace - Memorial Hospital of Rhode IslandPaul F. Malloy - Brown UniversityButler Hospital - Brown University
- Resource Type
- Journal article
- Publication Details
- Assessment (Odessa, Fla.), Vol.3(3), pp.327-337
- DOI
- 10.1177/1073191196003003012
- ISSN
- 1073-1911
- eISSN
- 1552-3489
- Language
- English
- Date published
- 09/1996
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984383909002771
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