Journal article
Frontal and Temporal Structural Connectivity Is Associated with Social Communication Impairment Following Traumatic Brain Injury
Journal of the International Neuropsychological Society, Vol.22(7), pp.705-716
08/2016
DOI: 10.1017/S1355617716000539
PMCID: PMC5823263
PMID: 27405965
Abstract
Objectives: Although it has been well documented that traumatic brain injury (TBI) can result in communication impairment, little work to date has examined the relationship between social communication skills and structural brain integrity in patients with TBI. The aim of the current study was to investigate the association between self- and other-perceived communication problems and white matter integrity in patients with mild to severe TBI. Methods: Forty-four individuals (TBI=24) and people with whom they frequently communicate, as well as demographically matched normal healthy comparisons (NC) and their frequent communication partners, were administered, respectively, the La-Trobe Communication Questionnaire Self form (LCQ-SELF) and Other form (LCQ-OTHER). In addition, diffusion tensor imaging data were collected, and fractional anisotropy (FA) measures were extracted for each lobe in both hemispheres. Results: Within the TBI group, but not within the NC group, participants who were perceived by their close others as having more communication problems had lower FA in the left frontal and temporal lobes (p<.01), but not in other brain regions. Conclusions: Frontotemporal white matter microstructural integrity is associated with social communication abilities in adults with TBI. This finding contributes to our understanding of the mechanisms leading to communication impairment following TBI and can inform the development of new neuromodulation therapies as well as diagnostic tools. (JINS, 2016, 22, 705–716)
Details
- Title: Subtitle
- Frontal and Temporal Structural Connectivity Is Associated with Social Communication Impairment Following Traumatic Brain Injury
- Creators
- Arianna Rigon - Interdisciplinary Neuroscience Program, The University of Iowa, Iowa City, IowaMichelle W Voss - Interdisciplinary Neuroscience Program, The University of Iowa, Iowa City, IowaLyn S Turkstra - Department of Communication Sciences and Disorders, The University of Wisconsin – Madison, WisconsinBilge Mutlu - Department of Computer Sciences, The University of Wisconsin – Madison, WisconsinMelissa C Duff - Interdisciplinary Neuroscience Program, The University of Iowa, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of the International Neuropsychological Society, Vol.22(7), pp.705-716
- DOI
- 10.1017/S1355617716000539
- PMID
- 27405965
- PMCID
- PMC5823263
- NLM abbreviation
- J Int Neuropsychol Soc
- ISSN
- 1355-6177
- eISSN
- 1469-7661
- Publisher
- Cambridge University Press; New York, USA
- Number of pages
- 12
- Language
- English
- Date published
- 08/2016
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984002343202771
Metrics
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