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Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17): PPND family. A longitudinal videotape demonstration
Journal article   Peer reviewed

Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17): PPND family. A longitudinal videotape demonstration

Z K Wszolek, R H Kardon, E C Wolters and R F Pfeiffer
Movement disorders, Vol.16(4), pp.756-760
07/2001
DOI: 10.1002/mds.1131
PMID: 11481705

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Abstract

Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), characterized by an autosomal dominant inheritance pattern, has recently been recognized as a distinct entity that can display a confusingly broad clinical phenotype. The pallido-ponto-nigral degeneration (PPND) variant is the prototypical example of the parkinsonism-predominant pattern of FTDP-17. A longitudinal videotape demonstration of the clinical progression of this entity in a single individual, along with brief videotape segments from three additional affected individuals, is presented in order to facilitate recognition of this disorder.
Videotape Recording Follow-Up Studies Humans Middle Aged Parkinsonian Disorders - diagnosis Dementia - diagnosis Male Dementia - genetics Neurologic Examination Chromosomes, Human, Pair 17 Adult Parkinsonian Disorders - genetics Genetic Linkage - genetics

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