Journal article
Full-length sequence of hepatitis B virus belonging to genotype H identified in a Japanese patient with chronic hepatitis
Japanese journal of infectious diseases, Vol.58(4), pp.244-246
08/2005
PMID: 16116261
Abstract
We have isolated and cloned the full-length nucleotide sequence of the hepatitis B virus (HBV) genome (denoted HBV-IM806-2) recovered from a Japanese patient with chronic hepatitis. This patient had a history of travel to Bangkok, Thailand, and then suffered the onset of acute hepatitis B 3 months after his return to Japan. The HBV-IM806-2 isolate was composed of 3,215 nucleotides and showed the highest similarity to genotype H of HBV. Interestingly, 24 amino acid residues specific for genotype H were identified throughout the full genome sequence. Furthermore, phylogenetic analysis based on the full genome sequence confirmed that IM806-2 belonged to genotype H and was more closely related to the prototype of the Los Angeles strain than to the Nicaragua strain.
Details
- Title: Subtitle
- Full-length sequence of hepatitis B virus belonging to genotype H identified in a Japanese patient with chronic hepatitis
- Creators
- Akira Nakajima - Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, JapanMitsugu UsuiTran Thien Tuan HuyNaomi Khaing Than HlaingNaohiko MasakiTetsutaro SataKenji Abe
- Resource Type
- Journal article
- Publication Details
- Japanese journal of infectious diseases, Vol.58(4), pp.244-246
- PMID
- 16116261
- ISSN
- 1344-6304
- eISSN
- 1884-2836
- Language
- English
- Date published
- 08/2005
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984094589302771
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