Journal article
Functional Imaging of Audio-Visual Selective Attention in Monkeys and Humans: How do Lapses in Monkey Performance Affect Cross-Species Correspondences?
Cerebral cortex (New York, N.Y. 1991), Vol.27(6), pp.3471-3484
06/01/2017
DOI: 10.1093/cercor/bhx092
PMCID: PMC5654311
PMID: 28419201
Abstract
The cross-species correspondences and differences in how attention modulates brain responses in humans and animal models are poorly understood. We trained 2 monkeys to perform an audio-visual selective attention task during functional magnetic resonance imaging (fMRI), rewarding them to attend to stimuli in one modality while ignoring those in the other. Monkey fMRI identified regions strongly modulated by auditory or visual attention. Surprisingly, auditory attention-related modulations were much more restricted in monkeys than humans performing the same tasks during fMRI. Further analyses ruled out trivial explanations, suggesting that labile selective-attention performance was associated with inhomogeneous modulations in wide cortical regions in the monkeys. The findings provide initial insights into how audio-visual selective attention modulates the primate brain, identify sources for "lost" attention effects in monkeys, and carry implications for modeling the neurobiology of human cognition with nonhuman animals.
Details
- Title: Subtitle
- Functional Imaging of Audio-Visual Selective Attention in Monkeys and Humans: How do Lapses in Monkey Performance Affect Cross-Species Correspondences?
- Creators
- Teemu Rinne - Aalto UniversityRoss S Muers - Newcastle UniversityEmma Salo - University of HelsinkiHeather Slater - Newcastle UniversityChristopher I Petkov - University of Newcastle Australia
- Resource Type
- Journal article
- Publication Details
- Cerebral cortex (New York, N.Y. 1991), Vol.27(6), pp.3471-3484
- DOI
- 10.1093/cercor/bhx092
- PMID
- 28419201
- PMCID
- PMC5654311
- NLM abbreviation
- Cereb Cortex
- ISSN
- 1047-3211
- eISSN
- 1460-2199
- Grant note
- BB/J009849/1 / Biotechnology and Biological Sciences Research Council NC/K000608/1 / National Centre for the Replacement, Refinement and Reduction of Animals in Research 102961/Z/13/Z / Wellcome Trust WT092606AIA / Wellcome Trust
- Language
- English
- Date published
- 06/01/2017
- Academic Unit
- Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
- Record Identifier
- 9984360132302771
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