Journal article
Functional Variants in NOS1 and NOS2A Are Not Associated with Progressive Hearing Loss in Ménière's Disease in a European Caucasian Population
DNA and cell biology, Vol.30(9), pp.699-708
09/01/2011
DOI: 10.1089/dna.2011.1259
PMID: 21612410
Abstract
Hearing loss in Ménière's disease (MD) is associated with loss of spiral ganglion neurons and hair cells. In a guinea pig model of endolymphatic hydrops, nitric oxide synthases (NOS) and oxidative stress mediate loss of spiral ganglion neurons. To test the hypothesis that functional variants of
Details
- Title: Subtitle
- Functional Variants in NOS1 and NOS2A Are Not Associated with Progressive Hearing Loss in Ménière's Disease in a European Caucasian Population
- Creators
- Irene Gazquez - 2Department of Immunology, Hospital Virgen de las Nieves, University of Granada, Granada, SpainJose A Lopez-Escamez - 3Otology and Neurotology Group CTS495, Department of Otolaryngology, Hospital de Poniente, El Ejido, Almería, SpainAntonia Moreno - 2Department of Immunology, Hospital Virgen de las Nieves, University of Granada, Granada, SpainColleen A Campbell - 4Department of Otolaryngology, University of Iowa, Iowa City, IowaNicole C Meyer - 4Department of Otolaryngology, University of Iowa, Iowa City, IowaJohn P Carey - 5Departments of Otolaryngology—Head and Neck Surgery, Biomedical Engineering, and Neuroscience, Johns Hopkins University, Baltimore, MarylandLloyd B Minor - 5Departments of Otolaryngology—Head and Neck Surgery, Biomedical Engineering, and Neuroscience, Johns Hopkins University, Baltimore, MarylandBruce J Gantz - 4Department of Otolaryngology, University of Iowa, Iowa City, IowaMarlan R Hansen - 4Department of Otolaryngology, University of Iowa, Iowa City, IowaCharles C Della Santina - 5Departments of Otolaryngology—Head and Neck Surgery, Biomedical Engineering, and Neuroscience, Johns Hopkins University, Baltimore, MarylandIsmael Aran - 6Department of Otolaryngology, Complejo Hospitalario de Pontevedra, Pontevedra, SpainAndres Soto-Varela - 7Division of Otoneurology, Department of Otorhinolaryngology, Hospital Clinico Universitario, Santiago de Compostela, Santiago, SpainSofia Santos - 7Division of Otoneurology, Department of Otorhinolaryngology, Hospital Clinico Universitario, Santiago de Compostela, Santiago, SpainAngel Batuecas - 8Department Otolaryngology, Hospital Universitario Salamanca, Salamanca, SpainHerminio Perez-Garrigues - 9Division of Otoneurology, Department of Otorhinolaryngology, Hospital La Fe, Valencia, SpainAlicia Lopez-Nevot - 10Otology and Neurotology Group CTS495, Department of Otolaryngology, Hospital Virgen de las Nieves, University of Granada, Granada, SpainRichard J.H Smith - 4Department of Otolaryngology, University of Iowa, Iowa City, IowaMiguel A Lopez-Nevot - 2Department of Immunology, Hospital Virgen de las Nieves, University of Granada, Granada, Spain
- Resource Type
- Journal article
- Publication Details
- DNA and cell biology, Vol.30(9), pp.699-708
- DOI
- 10.1089/dna.2011.1259
- PMID
- 21612410
- NLM abbreviation
- DNA Cell Biol
- ISSN
- 1044-5498
- eISSN
- 1557-7430
- Publisher
- Mary Ann Liebert, Inc
- Language
- English
- Date published
- 09/01/2011
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Molecular Physiology and Biophysics; Anatomy and Cell Biology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Cardiovascular Medicine; Neurosurgery; Otolaryngology; Internal Medicine
- Record Identifier
- 9984006358602771
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