Journal article
Functional organization of the primary motor cortex characterized by event-related fMRI during movement preparation and execution
Neuroscience letters, Vol.337(2), pp.69-72
2003
DOI: 10.1016/s0304-3940(02)01236-3
PMID: 12527390
Abstract
Neuronal recording and neuroimaging studies have shown that the primary motor area (M1) not only participates in motor execution, but is also engaged during movement preparation. The purpose of the present study was to map the distribution of the preparation- and execution-related activity within the contralateral M1 using functional magnetic resonance imaging. Eleven subjects performed a delayed sequential finger movement task, in which a CUE signal indicated a movement sequence in advance of an imperative GO signal. The hemodynamic response related to the CUE and GO signals decreased in a linear fashion across the central sulcus, with activity greater along the lateral extent compared to the medial extent. This decrease was especially evident in the epoch following the CUE. Our data reveal a pattern of functional organization within M1 related to the preparation and execution of movement sequences.
Details
- Title: Subtitle
- Functional organization of the primary motor cortex characterized by event-related fMRI during movement preparation and execution
- Creators
- Yufeng Zang - Laboratory for Higher Brain Function, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, ChinaFucang Jia - Laboratory for Higher Brain Function, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, ChinaXuchu Weng - Laboratory for Higher Brain Function, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, ChinaEnzhong Li - Department of MRI, Shougang General Hospital, Beijing 100041, ChinaShengzhong Cui - Laboratory for Higher Brain Function, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, ChinaYufeng Wang - Institute of Mental Health, Peking University, Beijing 100083, ChinaEliot Hazeltine - Department of Psychology, University of California Berkeley, CA 94720, USARichard Ivry - Department of Psychology, University of California Berkeley, CA 94720, USA
- Resource Type
- Journal article
- Publication Details
- Neuroscience letters, Vol.337(2), pp.69-72
- Publisher
- Elsevier Ireland Ltd
- DOI
- 10.1016/s0304-3940(02)01236-3
- PMID
- 12527390
- ISSN
- 0304-3940
- eISSN
- 1872-7972
- Language
- English
- Date published
- 2003
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984070781002771
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