Journal article
Gas chromatographic-mass spectrometric investigation of four commercial pristane (2.6.10.14-tetramethylpentadecane) preparations used for plasmacytoma induction in BALB/c mice
Archiv fur Geschwulstforschung, Vol.59(6), pp.415-422
1989
PMID: 2596957
Abstract
The most widely studied model of plasmacytomagenesis is the induction of plasmacytomas by intraperitoneal injections of pure alkanes such as pristane (2.6.10.14-tetramethylpentadecane). The presence of small amounts of genotoxic contaminants, that could contribute to the complex oncogenic process, in commercial pristane preparations has not been completely ruled out. Therefore, we conducted a chemical analysis of different pristane preparations applying a combined GC/MS technique, but were not capable of identifying any obvious or putative genotoxic/cancerogenic contaminants.
Details
- Title: Subtitle
- Gas chromatographic-mass spectrometric investigation of four commercial pristane (2.6.10.14-tetramethylpentadecane) preparations used for plasmacytoma induction in BALB/c mice
- Creators
- S Janz - Institute of Clinical Immunology, Faculty of Medicine, Karl Marx University LeipzigT BirkenfeldR HerzschuhH Storch
- Resource Type
- Journal article
- Publication Details
- Archiv fur Geschwulstforschung, Vol.59(6), pp.415-422
- PMID
- 2596957
- ISSN
- 0003-911X
- Language
- English
- Date published
- 1989
- Academic Unit
- Pathology
- Record Identifier
- 9984083207902771
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