Gastrointestinal pathologists' perspective on managing risk in the distal esophagus: convergence on a pragmatic approach

Andrew M Bellizzi; Sara Hafezi-Bakhtiari; Maria Westerhoff; E Celia Marginean; Robert H Riddell

doi:10.1111/nyas.13680

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Gastrointestinal pathologists' perspective on managing risk in the distal esophagus: convergence on a pragmatic approach

Journal article

Peer reviewed

Gastrointestinal pathologists' perspective on managing risk in the distal esophagus: convergence on a pragmatic approach

Andrew M Bellizzi, Sara Hafezi-Bakhtiari, Maria Westerhoff, E Celia Marginean and Robert H Riddell

Annals of the New York Academy of Sciences, Vol.1434(1), pp.35-45

12/2018

DOI: 10.1111/nyas.13680

PMID: 29749623

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Abstract

Here, we discuss recent updates and a continuing controversy in the diagnosis and management of Barrett's esophagus, specifically the recommendation that the irregular Z-line not be biopsied, the diminished status of ultrashort-segment Barrett's esophagus, the evidence basis for excluding and including the requirement of goblet cells for the diagnosis of Barrett's esophagus, and the conclusion that histologically confirmed low-grade dysplasia is best managed with endoscopic ablation rather than surveillance. We reference the American Gastroenterological Association and College of Gastroenterology and the British Society of Gastroenterology guidelines throughout, with the thesis that the field is converging on the concept of applying scarce medical resources to the diagnosis, surveillance, and therapy of patients most likely to derive benefit.

Esophagus - physiopathology

Esophagus - pathology

Barrett Esophagus - pathology

Barrett Esophagus - physiopathology

Barrett Esophagus - therapy

Humans

Barrett Esophagus - diagnosis

Pathology, Clinical

Risk Management

Details

Title: Subtitle: Gastrointestinal pathologists' perspective on managing risk in the distal esophagus: convergence on a pragmatic approach
Creators: Andrew M Bellizzi - Department of Pathology, University of Iowa Hospitals and Clinics and Carver College of Medicine, Iowa City, Iowa
Sara Hafezi-Bakhtiari - Department of Pathology, University Health Network, Toronto, Ontario, Canada
Maria Westerhoff - Department of Pathology, University of Michigan, Ann Arbor, Michigan
E Celia Marginean - Department of Pathology, University of Ottawa, Ottawa, Ontario, Canada
Robert H Riddell - Department of Pathology, Mount Sinai Hospital, Toronto, Ontario, Canada
Resource Type: Journal article
Publication Details: Annals of the New York Academy of Sciences, Vol.1434(1), pp.35-45
DOI: 10.1111/nyas.13680
PMID: 29749623
NLM abbreviation: Ann N Y Acad Sci
ISSN: 0077-8923
eISSN: 1749-6632
Publisher: Wiley; United States
Grant note: P30 CA086862 / NCI NIH HHS
Language: English
Date published: 12/2018
Academic Unit: Pathology
Record Identifier: 9984047692802771

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