Gender and Racial/Ethnic Disparities in Social Determinants of Health and Subjective Cognitive Decline: The Mediating Role of Depression

Monique J Brown; Chantaezia Joseph; Titilayo James; Mohammad Rifat Haider; Whitney E Zahnd; Steven A Cohen

doi:10.3928/00989134-20220110-01

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Gender and Racial/Ethnic Disparities in Social Determinants of Health and Subjective Cognitive Decline: The Mediating Role of Depression

Journal article

Peer reviewed

Gender and Racial/Ethnic Disparities in Social Determinants of Health and Subjective Cognitive Decline: The Mediating Role of Depression

Monique J Brown, Chantaezia Joseph, Titilayo James, Mohammad Rifat Haider, Whitney E Zahnd and Steven A Cohen

Journal of gerontological nursing, Vol.48(2), pp.13-22

02/2022

DOI: 10.3928/00989134-20220110-01

PMCID: PMC9003396

PMID: 35103521

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https://www.ncbi.nlm.nih.gov/pmc/articles/9003396View

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Abstract

Social determinants of health (SDOH) may be associated with subjective cognitive decline (SCD), which is a precursor for Alzheimer's disease. The main aims of the current study were to examine the association between SDOH and SCD; to determine if there is an indirect pathway among SDOH, depression, and SCD; and to examine the related gender and racial/ethnic disparities. Cross-sectional data were obtained from the 2017 Behavioral Risk Factor Surveillance System Survey ( = 6,509; 2,530 men and 3,978 women aged ≥45 years). Path analyses (stratified by gender and race) were used to determine the relationship between a SDOH index, depression, and SCD. After controlling for gender, age, income, education, employment, and other health-related behaviors, SDOH were positively associated with SCD among the overall population, men, and White populations. SDOH were associated with depression, and depression was associated with SCD among men, women, and White and Black populations. After adjustment for confounders, the indirect pathway among SDOH, depression, and SCD was statistically significant for men (β = 0.035, < 0.001), women (β = 0.040, < 0.001), White populations (β = 0.034, < 0.001), and Black populations (β = 0.036, = 0.026). Gender and racial/ethnic disparities existed in the relationship among SDOH, depression, and SCD. Future research should assess alternative mediational pathways between SDOH and SCD. [ (2), 13-22.].

Cognitive Dysfunction

Cross-Sectional Studies

Depression - epidemiology

Female

Hispanic or Latino

Humans

Male

Social Determinants of Health

Details

Title: Subtitle: Gender and Racial/Ethnic Disparities in Social Determinants of Health and Subjective Cognitive Decline: The Mediating Role of Depression
Creators: Monique J Brown
Chantaezia Joseph
Titilayo James
Mohammad Rifat Haider
Whitney E Zahnd
Steven A Cohen
Resource Type: Journal article
Publication Details: Journal of gerontological nursing, Vol.48(2), pp.13-22
DOI: 10.3928/00989134-20220110-01
PMID: 35103521
PMCID: PMC9003396
NLM abbreviation: J Gerontol Nurs
ISSN: 0098-9134
eISSN: 1938-243X
Language: English
Date published: 02/2022
Academic Unit: Health Management and Policy
Record Identifier: 9984221641302771

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